FITC标记的黑色素瘤相关抗原抗体

FITC标记的黑色素瘤相关抗原抗体

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  • ¥2980
  • LMAI Bio
  • LM-1523R-FITC
  • 中国/美国/欧洲
  • 2025年07月11日
  • Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200
  • Human
  • Human
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-1523R-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-CD63/FITC

    • 抗体名

      Anti-CD63/FITC

    • 标记物

      FITC标记

    • 宿主

      Human

    • 适应物种

      Human

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul

    FITC标记的黑色素瘤相关抗原抗体
    英文名称 Anti-CD63/FITC
    中文名称 FITC标记的黑色素瘤相关抗原抗体
    别    名 Lysosomal associated membrane protein 3; CD63 antigen; CD63 antigen melanoma 1 antigen; CD63 molecule; granulophysin; LAMP 3; LAMP3; lysosome associated membrane glycoprotein 3; CD 63; CD63; CD63 antigen (melanoma 1 antigen); CD63_HUMAN; gp55; granulophysin; LAMP-3; LIMP; Lysosomal-associated membrane protein 3; Melanoma-associated antigen ME491; NGA; Ocular melanoma-associated antigen; PTLGP40; Tetraspanin-30; Tspan-30; Mast cell antigen AD1; ME491; melanoma 1 antigen; Melanoma associated antigen ME491; Melanoma associated antigen MLA1; MGC72893; MLA 1; MLA1; ocular melanoma associated antigen; OMA81H; Tetraspanin 30; Tspan 30; TSPAN30; Tumor biomarkers; Platelets markers.  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    研究领域 肿瘤  心血管  免疫学  细胞类型标志物  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, 
    产品应用 Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 26kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human CD63
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene. Alternative splicing results in multiple transcript variants encoding different proteins.

    Function:
    This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Note=Also found in Weibel-Palade bodies of endothelial cells. Located in platelet dense granules.

    Tissue Specificity:
    Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages.

    Similarity:
    Belongs to the tetraspanin (TM4SF) family.

    Database links:

    Entrez Gene: 967 Human

    Omim: 155740 Human

    SwissProt: P08962 Human

    Unigene: 445570 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

    CD63为溶酶体膜糖蛋白也是一种细胞表面糖蛋白,可表达在多种细胞的表面和胞浆内,血小板活化后即转移至膜表面。
    CD63—又称黑色素瘤相关抗原MLA1和整合素形成复合物。是血液血小板活化的标志。与一些肿瘤的进展也有关联。

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