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文献和实验网络 四、Cadherin家族 Takeichi最早发现一种介导细胞间相互聚集的粘附分子,在有Ca 2+ 存在时可以抵抗蛋白酶的水解作用,以后又发现两种作用和特性均与其类似的粘附分子,它们的氨基酸序列也有同源性,遂将其命名为Cadherin(Ca 2+
Cadherin-Mediated Cell-Cell Interactions
-4) Human, mouse, chicken, Xenopus Eye (retina, pigmented epithelium), brain, skeletal muscle, pancreas, gastrointestinal tract VE-Cadherin (cadherin-5
Tracking the Transport of E-Cadherin to and From the Plasma Membrane
, it is also a key occurrence in many diseases, including cancers of epithelial origin E-cadherin is a central component of adherens junctions (AJs), which act as structural and signaling hubs in epithelial cells that oppose EMT. The loss of E-cadherin
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