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Recombinant Human Serpin E1 (C

-6His)(Cat. No.:C537)
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  • ¥1200
  • novoprotein
  • C537
  • C537
  • 2025年10月14日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保质期

      Recombinant Human Serpin E1 (C-6His)

    • 保存条件

      C537

    • 库存

      C537

    • 供应商

      Recombinant Human Serpin E1 (C-6His)

    • 英文名

      Recombinant Human Serpin E1 (C-6His)

    • 规格

      10ug

    Recombinant Human Serpin E1 (C-6His)(Cat. No.:C537)
    产品描述
    Recombinant Human Serine Protease Inhibitor-clade E1 is produced by our Mammalian expression system and the target gene encoding Val24-Pro402 is expressed with a 6His tag at the C-terminus.
    产品细节图片1 蛋白编号
    P05121
    产品细节图片2 产品别称
    Plasminogen Activator Inhibitor 1; PAI; PAI-1; Endothelial Plasminogen Activator Inhibitor; Serpin E1; SERPINE1; PAI1; PLANH1
    产品细节图片3 分子量
    43.82 KDa
    产品细节图片4 表观分子量
    48 KDa, reducing conditions
    产品细节图片5 剂型描述
    Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
    产品细节图片6 内毒素
    Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
    产品细节图片7 纯度
    产品细节图片8 Greater than 95% as determined by reducing SDS-PAGE.
    产品细节图片9 复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in 4mM HCl.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    产品细节图片10 保存条件
    • Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    • Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    产品细节图片11 运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
    产品细节图片12 产品背景
    Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. They are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpin E1 is a secreted protein which belongs to the Serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. Defects in SERPINE1 are characterized by abnormal bleeding due to Serpin E1 defect in the plasma. High concentrations of Serpin E1 have been associated with thrombophilia which is an autosomal dominant disorder in which affected individuals are prone to develop serious spontaneous thrombosis.
    仅供科研使用,不可直接应用于人体。

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