Product overview Description Anti-RPL13A rabbit polyclonal antibody Applications ELISA, IHC Immunogen Fusion protein of human RPL13A Reactivity Human, Mouse, Rat Content 1.68 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol RPL13A Full name ribosomal protein L13a Synonyms L13A; TSTA1 Swissprot P40429
Target Background Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L13P family of ribosomal proteins that is a component of the 60S subunit. The encoded protein also plays a role in the repression of inflammatory genes as a component of the IFN-gamma-activated inhibitor of translation (GAIT) complex. This gene is co-transcribed with the small nucleolar RNA genes U32, U33, U34, and U35, which are located in the second, fourth, fifth, and sixth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Applications Immunohistochemistry Predicted cell location: Cytoplasm or Nucleus Positive control: Human tonsil Recommended dilution: 50-300 Predicted cell location: Cytoplasm or Nucleus Positive control: Human thyroid cancer Recommended dilution: 50-300
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using ml225645(RPL13A Antibody) at dilution 1/95, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ml225645(RPL13A Antibody) at dilution 1/95, on the right is treated with fusion protein. (Original magnification: ×200)