Calcium/calmodulin dependent protein kinase 1 G; Calcium/calmodulin-dependent protein kinase type 1G; CaM kinase I gamma; CaM kinase IG; CaM-KI gamma; CaMKI gamma; CAMK1G; VWS1; CaMKI-gamma; CaMKIG; CaMK-like CREB kinase III; CLICK III; KCC1G_HUMAN.
规格价格
100ul/2980元 购买 大包装/询价
说 明 书
100ul
研究领域
细胞生物 神经生物学 信号转导 生长因子和激素 激酶和磷酸酶
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Mouse, Rat,
产品应用
IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
53kDa
细胞定位
细胞膜
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human Camk1g
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍
background: CaMKI gamma is a Calcium/calmodulin-dependent protein kinase which belongs to a proposed calcium-triggered signaling cascade. In vitro it phosphorylates transcription factor CREB1. It has been proposed that CaMKI gamma is involved in dendritic outgrowth mediated by CaM-dependant protein kinase kinase.
Function: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription factor CREB1 (By similarity).
Tissue Specificity: Mainly expressed in brain with small amounts in skeletal muscles, kidney, spleen and liver. Strongly expressed in forebrain neocortex, striatum and limbic system.
Post-translational modifications: May be prenylated on Cys-473.
Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. Contains 1 protein kinase domain.
Database links:
Entrez Gene: 57172 Human
Entrez Gene: 215303 Mouse
Entrez Gene: 448849 Pig
Entrez Gene: 171358 Rat
SwissProt: Q96NX5 Human
SwissProt: Q91VB2 Mouse
SwissProt: Q7TNJ7 Rat
Unigene: 199068 Human
Unigene: 40329 Mouse
Unigene: 91453 Rat
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.