Product overview
Description Anti-COPE rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human COPE
Reactivity Human, Mouse
Content 0.84 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol COPE
Full name coatomer protein complex subunit epsilon
Synonyms epsilon-COP
Swissprot O14579
Target Background
The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.