Product overview Description Anti-CIRBP rabbit polyclonal antibody Applications ELISA, IHC Immunogen Full length fusion protein Reactivity Human, Mouse, Rat Content 0.48 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol CIRBP Full name cold inducible RNA binding protein Synonyms CIRP Swissprot Q14011
Target Background Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.