Product overview
Description Anti-CIAO1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human CIAO1
Reactivity Human, Mouse, Rat
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CIAO1
Full name cytosolic iron-sulfur assembly component 1
Synonyms CIA1; WDR39
Swissprot O76071
Target Background
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.