Product overview Description Anti-AGPS rabbit polyclonal antibody Applications ELISA, IHC Immunogen Fusion protein of human AGPS Reactivity Human, Mouse, Rat Content 0.2 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol AGPS Full name alkylglycerone phosphate synthase Synonyms ADAS; ADPS; ADAP-S; ADHAPS; ALDHPSY Swissprot O00116
Target Background This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome.
Applications Immunohistochemistry Predicted cell location: Cytoplasm Positive control: Human gasrtic cancer Recommended dilution: 25-100 Predicted cell location: Cytoplasm Positive control: Human liver cancer Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using ml221581(AGPS Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml221581(AGPS Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)