Anti-THEM5 antibody

Anti-THEM5 antibody

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  • 询价
  • 晶抗生物
  • JK223754
  • 上海
  • 2025年07月11日
  • 科研试验
  • Rabbit
  • Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Sheep
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    • 详细信息
    • 技术资料
    • 供应商

      上海晶抗生物工程有限公司

    • 库存

      大量

    • 克隆性

      多克隆

    • 保质期

      1年

    • 抗体英文名

      Anti-THEM5 antibody

    • 宿主

      Rabbit

    • 适应物种

      Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Sheep

    • 应用范围

      科研试验

    • 保存条件

      -20°C

    • 规格

      25 μl/100 μl/200 μl

    Anti-THEM5 antibody

    Anti-THEM5 antibody

    Cat. No.    JK223754       
    Package    25 μl/100 μl/200 μl
    Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

    Product overview
    Description                   Anti-THEM5 rabbit polyclonal antibody
    Applications        ELISA, IHC 
    Immunogen               Full length fusion protein
    Reactivity                 Human
    Content                     0.7 mg/ml
    Host species               Rabbit
    Ig class                  Immunogen-specific rabbit IgG
    Purification                 Antigen affinity purification

    Target information
    Symbol                 THEM5
    Full name                 thioesterase superfamily member 5
    Synonyms    ACOT15
    Swissprot    Q8N1Q8

    Target Background
    THEM5 (thioesterase superfamily member 5) is a 247 amino acid protein that belongs to the thioesterase superfamily. The gene that encodes THEM5 contains nearly 8,000 bases and maps to human chromosome 1q21.3. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleyl-CoA and other unsaturated long-chain fatty acid-CoA esters. Plays an important role in mitochondrial fatty acid metabolism, and in remodeling of the mitochondrial lipid cardiolipin. Required for normal mitochondrial function.

     

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    资料下载:

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