- 询价
- gelatins
- JLC220906
- 上海
- 2025年07月11日
- Rabbit
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- 详细信息
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-KLK7 antibody
- 宿主：
Rabbit
- 浓度：
0.485 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Anti-KLK7 antibody
Cat. No. JLC220906
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-KLK7 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human KLK7
Reactivity Human, Mouse
Content 0.485 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol KLK7
Full name kallikrein-related peptidase 7
Synonyms hK7, SCCE, PRSS6
Swissprot P49862
Target Background
This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm, Nucleus
Positive control: Human esophagus cancer
Recommended dilution: 25-100 Predicted cell location: Cytoplasm, Nucleus
Positive control: Human colon cancer
Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ml220906(KLK7 Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using ml220906(KLK7 Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200)
Western blotting
Predicted band size:28 kDa
Positive control:Mouse brain and kidney tissue
Recommended dilution: 500-2000
Gel: 12%SDS-PAGE
Lysate: 40 μg
Lane 1-2: Mouse brain tissue, Mouse kidney tissue
Primary antibody: ml220906(KLK7 Antibody) at dilution 1/600
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 20 seconds
ELISA
Recommended dilution: 2000-5000
Cat. No. JLC220906
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-KLK7 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human KLK7
Reactivity Human, Mouse
Content 0.485 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol KLK7
Full name kallikrein-related peptidase 7
Synonyms hK7, SCCE, PRSS6
Swissprot P49862
Target Background
This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm, Nucleus
Positive control: Human esophagus cancer
Recommended dilution: 25-100 Predicted cell location: Cytoplasm, Nucleus
Positive control: Human colon cancer
Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ml220906(KLK7 Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using ml220906(KLK7 Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200)
Western blotting
Predicted band size:28 kDa
Positive control:Mouse brain and kidney tissue
Recommended dilution: 500-2000
Gel: 12%SDS-PAGE
Lysate: 40 μg
Lane 1-2: Mouse brain tissue, Mouse kidney tissue
Primary antibody: ml220906(KLK7 Antibody) at dilution 1/600
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 20 seconds
ELISA
Recommended dilution: 2000-5000
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Anti-KLK7 antibody
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