Anti-LILRB2 antibody

Anti-LILRB2 antibody

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  • 询价
  • gelatins
  • JLC220886
  • 上海
  • 2025年07月14日
  • Rabbit
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    • 详细信息
    • 技术资料
    • 供应商

      江西江蓝纯生物试剂有限公司

    • 库存

      大量

    • 克隆性

      多克隆

    • 保质期

      1年

    • 抗体英文名

      Anti-LILRB2 antibody

    • 宿主

      Rabbit

    • 浓度

      0.7 mg/ml

    • 保存条件

      -20°C

    • 规格

      25 μl/100 μl/200 μl

    Anti-LILRB2 antibody

    Cat. No.     JLC220886        
    Package    25 μl/100 μl/200 μl
    Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

    Product overview
    Description                   Anti-LILRB2 rabbit polyclonal antibody
    Applications        ELISA, IHC 
    Immunogen               Fusion protein of human LILRB2
    Reactivity                 Human
    Content                     0.7 mg/ml
    Host species               Rabbit
    Ig class                  Immunogen-specific rabbit IgG
    Purification                 Antigen affinity purification

    Target information
    Symbol                 LILRB2
    Full name                 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
    Synonyms    ILT4, LIR2, CD85D, LIR-2, MIR10, LILRA6, MIR-10
    Swissprot    Q8N423

    Target Background
    This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

    Applications
    Immunohistochemistry
    Predicted cell location: Cytoplasm
    Positive control: Human esophagus cancer
    Recommended dilution: 25-100    Predicted cell location: Cytoplasm
    Positive control: Human cervical cancer
    Recommended dilution: 25-100
                
    The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ml220886(LILRB2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)    The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using ml220886(LILRB2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)

    ELISA
    Recommended dilution: 1000-5000

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    资料下载:

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