Product overview Description Anti-FASTK rabbit polyclonal antibody Applications ELISA, IHC Immunogen Fusion protein of human FASTK Reactivity Human, Mouse Content 0.5 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol FASTK Full name fas-activated serine/threonine kinase Synonyms FAST Swissprot Q14296
Target Background The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.
Applications Immunohistochemistry Predicted cell location: Cytoplasm Positive control: Human gasrtic cancer Recommended dilution: 50-200 Predicted cell location: Cytoplasm Positive control: Human brain Recommended dilution: 50-200
The image is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using ml220624(FASTK Antibody) at dilution 1/30. (Original magnification: ×200) The image is immunohistochemistry of paraffin-embedded Human brain tissue using ml220624(FASTK Antibody) at dilution 1/30. (Original magnification: ×200)