Anti-LEP antibody

Anti-LEP antibody依托国家重点实验室建立，是由具有生命科学、生物技术背景及留学归国人员共同创办的，同心协力，尽展创意，致力于可持续发展、向社会尽责的企业宗旨，紧跟经营管理和科学技术发展的步伐，提升和加强市场竞争力，产品种类齐全、现货供应质量长期保障，欢迎各位新老客户来电咨询！

Anti-LEP antibody

Cat. No.    JK222615      
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-LEP rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Full length fusion protein
Reactivity                 Human, Mouse, Rat
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 LEP
Full name                 leptin
Synonyms    OB; OBS; LEPD
Swissprot    P41159

Target Background
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.