Product overview
Description Anti-GLUL rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human GLUL
Reactivity Human, Mouse, Rat
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol GLUL
Full name glutamate-ammonia ligase
Synonyms GS; GLNS; PIG43; PIG59
Swissprot P15104
Target Background
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. This gene is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in this gene are associated with congenital glutamine deficiency. Several alternatively spliced transcript variants have been found for this gene.