Product overview
Description Anti-UCHL5 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human UCHL5
Reactivity Human, Mouse
Content 0.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol UCHL5
Full name ubiquitin carboxyl-terminal hydrolase L5
Synonyms UCH37; CGI-70; INO80R; UCH-L5
Swissprot Q9Y5K5
Target Background
Ubiquitin carboxyl-terminal hydrolase isozyme L5 is an enzyme that in humans is encoded by the UCHL5gene. Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.