Product overview
Description Anti-ATG10 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human ATG10
Reactivity Human, Mouse
Content 0.8 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol ATG10
Full name autophagy related 10
Synonyms APG10; APG10L; pp12616
Swissprot Q9H0Y0
Target Background
Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form.