Product overview
Description Anti-TFF1 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human TFF1
Reactivity Human, Mouse
Content 0.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol TFF1
Full name Trefoil factor 1
Synonyms pS2; BCEI; HPS2; HP1.A; pNR-2; D21S21
Swissprot P04155
Target Background
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.