Product overview
Description Anti-IGF2BP3 rabbit polyclonal antibody
Applications ELISA, WB
Immunogen Fusion protein of human IGF2BP3
Reactivity Human, Mouse
Content 0.1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol IGF2BP3
Full name insulin-like growth factor 2 mRNA binding protein 3
Synonyms KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3
Swissprot O00425
Target Background
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.