生长抑素受体1抗体图片

生长抑素受体1抗体图片Anti-S6PDH/FITC 荧光素标记抗6-山梨醇脱酶抗体IgGMulti-class antibodies规格： 0.2ml
ShK(Stichodactyla helianthus Neurotoxin)-(Arg22) 海葵神经毒素(35肽)Multi-class antibodies规格： 0.1mg
基质金属蛋白酶-2抗体 Anti-MMP-2 0.1ml
14-3-3 zeta+delta 英文名称： 14-3-3 protein ζ/δ抗体 0.1ml
human Fibrinogen 英文名称： 羊抗人纤维蛋白原抗体 0.1ml
Rhesus antibody Rh phospho-PDHA1(Ser293) 化酸脱酶α1抗体 规格 0.1ml
ShK(Stichodactyla helianthus Neurotoxin)-(Arg22) 海葵神经毒素(35肽)Multi-class antibodies规格： 0.1mg
英文名称  Anti-SSTR1/Somatostatin Receptor 1
中文名称 生长抑素受体1抗体图片

别    名  somatostatin receptor 1; Somatostatin R1; Somatostatin receptor isoform 1; Somatostatin receptor type 1; SRIF 2; SRIF2; SSTR 1; SSTR1; Sstr1;SRIF-2; Smstr-1; Smstr1; sst1. 
生长抑素受体1抗体图片浓    度  1mg/1ml
规 格  0.1ml/100μg 0.2ml/200μg
抗体来源  Rabbit
克隆类型   polyclonal
交叉反应  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Guinea Pig
产品类型    一抗  
研究领域    神经生物学 细胞凋亡 生长因子和激素 细胞膜受体 G蛋白偶联受体
蛋白分子量  predicted molecular weight: 43kDa
性    状  Lyophilized or Liquid
免 疫 原   KLH conjugated synthetic peptide derived from human SSTR1 C-terminus
亚    型  IgG
纯化方法   affinity purified by Protein A
储 存 液   0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

生长抑素受体1抗体图片产品应用  WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复） 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
产品介绍 Somatostatin Receptor (SSTR) 1 is one of the five receptor subtypes termed SSTR 1 to 5. They are G-protein-coupled receptors characterized by seven transmembrane helices with an extracellular amino terminal domain and an intracellular carboxy terminus. These receptors are activated by somatostatin secreted by nerve and endocrine cells and function in the regulation of numerous physiological processes such as the secretion of insulin, glucagon and growth hormone. The SSTRs also play a role in cell growth induced by neuronal excitation in both the central and peripheral nervous system.
The Somatostatin family of receptors have five members, sst1-sst5, as well as two isoforms of Somatostatin receptor 2, sst2A and sst2B.
They are coupled to G protein and are involved in regulation of numerous processes including secretion of insulin, glucagons and growth hormone and excitation of neurons in central and peripheral nervous system.
Subunit : Interacts with SKB1.
Subcellular Location : Cell membrane; Multi-pass membrane protein.
Tissue Specificity : Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach.
Similarity : Belongs to the G-protein coupled receptor 1 family.


生长抑素受体1抗体图片抗体的鉴定：
1）抗体的效价鉴定：不管是用于诊断还是用于治疗,制备抗体的目的都是要求较高效价。不同的抗原制备的抗体,要求的效价不一。鉴定效价的方法很多,包括有试管凝集反应,琼脂扩散试验,酶联免疫吸附试验等。常用的抗原所制备的抗体一般都有约成的鉴定效价的方法,以资比较。如制备抗抗体的效价,一般就采用琼脂扩散试验来鉴定。
2）抗体的特异性鉴定：抗体的特异性是指与相应抗原或近似抗原物质的识别能力。抗体的特异性高,它的识别能力就强。衡量特异性通常以交叉反应率来表示。交叉反应率可用竞争抑制试验测定。以不同浓度抗原和近似抗原分别做竞争抑制曲线,计算各自的结合率,求出各自在IC50时的浓度,并按公式计算交叉反应率。 
如果所用抗原浓度IC50浓度为pg/管,而一些近似抗原物质的IC50浓度几乎是无穷大时,表示这一抗血清与其他抗原物质的交叉反应率近似为0,即该血清的特异性较好。
3）亲和力：是指抗体和抗原结合的牢固程度。亲和力的高低是由抗原分子的大小,抗体分子的结合位点与抗原决定簇之间立体构型的合适度决定的。有助于维持抗原抗体复合物稳定的分子间力有氢键,疏水键,侧链相反电荷基因的库仑力,范德华力和空间斥力。亲和力常以亲和常数K表示,K的单位是L/mol。抗体亲和力的测定对抗体的筛选,确定抗体的用途,验证抗体的均一性等均有重要意义。
种属：
兔抗单克隆抗体，鼠抗单克隆抗体。兔抗多克隆抗体。抗体的浓度为1mg/ml。 抗体及相关标记抗体：HRP标记抗体，Biotin标记抗体，Gold标记抗体，RBITC标记抗体，AP标记抗体,FITC标记抗体，Cy3标记抗体，Cy5标记抗体，Cy5.5标记抗体，Cy7标记抗体，PE标记抗体，PE-Cy3标记抗体，PE-Cy5标记抗体，PE-Cy5.5标记抗体，PE-Cy7标记抗体，APC标记抗体，AlexaFluor 350标记抗体，Alexa Fluor 488标记抗体，Alexa Fluor 555标记抗体，Alexa Fluor647标记抗体 抗体的交叉反应： 人，小鼠，大鼠，鸡 ，狗，猪，羊，牛，兔等...... 抗体的应用：可以用于做石蜡切片免疫组化，冰冻切片免疫组化，Elisa，WB，免疫荧光等实验。

HA tag HA tag标签多肽Multi-class antibodies规格： 0.5mg
TFRC Transferrin Receptor / TFRC / CD71 兔单抗 (PE) Human
Rhesus antibody Rh phospho-c-Raf(Ser339) 化原癌基因c-Raf抗体 规格 0.1ml
兔抗亲和素纯化抗体 1mg/10mg 国产
YES1 英文名称： 原癌基因酪酸蛋白激酶Yes1抗体 0.1ml
DRD4 英文名称： 多巴胺受体D4抗体 0.2ml
TFRC Transferrin Receptor / TFRC / CD71 兔单抗 (PE) Human
Syntaxin 6 英文名称： 突触融合蛋白6抗体 0.2ml
phospho-ERF (Thr526) 英文名称： 化转录因子ERF抗体 0.1ml
小鼠抗3-甘油醛脱酶单克隆抗体(内参抗体) Anti-GAPDH 0.1ml
Anti-VSV-G tag/FITC 荧光素标记VSV-G tag标签抗体IgGMulti-class antibodies规格： 0.2ml
Rhesus antibody Rh Phospho-Gab1 (Tyr627) 化接头蛋白Gab 1抗体 规格 0.1ml
CK 1/8/19 (Cytokeratin1/8/19; Keratin 1/8/19)peptide 细胞角蛋白1/8/19抗原Multi-class antibodies规格： 0.5mg
Certain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis. Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3. RIP3 contains an N terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, mediates TNFR1 induced apoptosis, and attenuates RIP and TNFR1 induced NF-kB activation. Over expression of RIP3 induces apoptosis and NF-kB activation. The messenger RNA of RIP3 is expressed in a subset of adult tissues.
Function : Essential for programmed necrosis in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production (By similarity).
Subunit : Interacts (via RIP homotypic interaction motif) with RIPK1 (via RIP homotypic interaction motif); this interaction induces RIPK1 phosphorylation and formation of a RIPK1-RIPK3 necrosis-inducing complex. Upon TNF-induced necrosis, the RIPK1-RIPK3 dimer further interacts with PGAM5 and MLKL; the formation of this complex leads to PGAM5 phosphorylation and increase in PGAM5 phosphatase activity. Binds TRAF2 and is recruited to the TNFR-1 signaling complex. Interacts with PYGL, GLUL and GLUD1; these interactions result in activation of these metabolic enzymes. Interacts with BIRC2/c-IAP1, BIRC3/c-IAP2 and XIAP/BIRC4.
Subcellular Location : Cytoplasm (By similarity). Cell membrane (By similarity). Mitochondrion (Potential).
Tissue Specificity : Highly expressed in the pancreas. Detected at lower levels in heart, placenta, lung and kidney. Isoform 3 is significantly increased in colon and lung cancers.
Post-translational modifications : RIPK1 and RIPK3 undergo reciprocal auto- and trans-phosphorylation. Phosphorylation of Ser-199 plays a role in the necroptotic function of RIPK3.
Polyubiquitinated with 'Lys-48' and 'Lys-63'-linked chains by BIRC2/c-IAP1 and BIRC3/c-IAP2, leading to activation of NF-kappa-B.
Similarity : Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Contains 1 protein kinase domain.
Database links : UniProtKB/Swiss-Prot: Q9Y572.2

Anti-NEP/FITC 荧光素标记脑啡肽酶抗体IgGMulti-class antibodies规格： 0.2ml
Mouse Anti-human VEGF/FITC 荧光素标记小鼠抗人VEGF单克隆抗体IgGMulti-class antibodies规格： 0.2ml
血管位蛋白样1/血管生成素样蛋白-1抗体 Anti-ANGPTL1/ANG-1 0.2ml
Mouse Anti-human IgG/Cy3 Cy3标记的小鼠抗人IgG 0.1ml
GALNT1 英文名称： 多肽N-乙酰基半乳糖转移酶1抗体 0.2ml
Rhesus antibody Rh procollagen type IIA Ⅱ型胶原α1抗体 规格 0.2ml
Mouse Anti-human VEGF/FITC 荧光素标记小鼠抗人VEGF单克隆抗体IgGMulti-class antibodies规格： 0.2ml
生长抑素受体1抗体图片PIWIL1(piwi-like 1) piwi 样1蛋白(抗原)Multi-class antibodies规格： 0.5mg
Anti-CD68 CD68抗体Multi-class antibodies规格： 0.2ml
Rhesus antibody Rh p150 CAF1 染色质组装因子1P155抗体 规格 0.2ml
SCGN Kit Human 人 SCGN / Secretagogin ELISA配对抗体 ELISA
TUG 英文名称： 腺泡状软组织肉瘤结构域蛋白ASPC抗体 0.2ml
CEND1 英文名称： 细胞周期通道和神经细胞分化蛋白1抗体 0.2ml
Anti-CD68 CD68抗体Multi-class antibodies规格： 0.2ml
生长抑素受体1抗体图片实验原理 :
（1）特异性结合抗原：抗体本身不能直接溶解或杀伤带有特异抗原的靶细胞，通常需要补体或吞噬细胞等共同发挥效应以清除病原微生物或导致病理损伤。然而，抗体可通过与病毒或毒素的特异性结合，直接发挥中和病毒的作用。
（2）活补体：IgM、IgG1、IgG2和IgG3可通过经典途径激活补体，凝聚的IgA、IgG4和IgE可通过替代途径激活补体。
（3）结合细胞：不同类别的免疫球蛋白，可结合不同种的细胞，参与免疫应答。
（4）可通过胎盘及粘膜：免疫球蛋白G（IgG）能通过胎盘进入胎儿血流中，使胎儿形成自然被动
免疫。免疫球蛋白A（IgA）可通过消化道及呼吸道粘膜，是粘膜局部抗感染免疫的主要因素。
（5）具有抗原性：抗体分子是一种蛋白质，也具有刺机体产生免疫应答的性能。不同的免疫球蛋白分子，各具有不同的抗原性。
（6）抗体对理化因子的抵抗力与一般球蛋白相同：不耐热，60～70℃即被破坏。各种酶及能使蛋白质凝固变性的物质，均能破坏抗体的作用。抗体可被中性盐类沉淀。在上常可用硫酸铵或硫酸钠从免疫血清中沉淀出含有抗体的球蛋白，再经透析法将其纯化。