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- 详细信息
- 技术资料
- 抗体名:
干燥症SSB/La抗体使用说明书
- 抗体英文名:
Anti-SSB/La
- 靶点:
详见说明书
- 浓度:
1mg/1ml
- 应用范围:
WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
- 宿主:
详见说明书
- 供应商:
上海博湖
- 库存:
大量
- 级别:
详见说明书
- 目录编号:
详见说明书
- 抗原来源:
Rabbit
- 保质期:
详见说明书
- 适应物种:
详见说明书
- 标记物:
详见说明书
- 克隆性:
多克隆
- 保存条件:
Store at -20 °C
- 形态:
详见说明书
- 亚型:
IgG
- 免疫原:
KLH conjugated synthetic peptide derived from human SSB C-terminus
- 规格:
0.2ml/200μg
干燥症SSB/La抗体使用说明书是用于化学反应、分析化验、研究实验、教学实验、化学配方使用的纯净化学品,产品品质卓越,价格实惠,多种规格供应,售后完善。
英文名称 Anti-SSB/La
中文名称 干燥症SSB/La抗体使用说明书
别 名 SSB; Lupus La protein homolog; La ribonucleoprotein; La autoantigen homolog; Sjogren syndrome type B antigen; LA_HUMAN.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human
产品类型 一抗
研究领域 免疫学
蛋白分子量 predicted molecular weight: 47kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human SSB C-terminus
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
干燥症SSB/La抗体使用说明书产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Lupus La protein (Sjogren syndrome type B antigen) (SS-B) (La ribonucleoprotein) (La autoantigen) plays a role in the transcription of RNA polymerase III. It is most probably a transcription termination factor. Binds to the 3' termini of virtually all nascent polymerase III transcripts. It is associated with precursor forms of RNA polymerase III transcripts including tRNA and 4.5S, 5S, 7S, and 7-2 RNAs. The phosphorylation sites are at the C-terminal part of the protein. Sera from patients with systemic lupus erythematosus(SLE) often contain antibodies that react with the normal cellular La protein as if this antigen was foreign.
Function : Binds to the 3' poly(U) terminii of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.
Subunit : Interacts with DDX15. May interact with RUFY1.
Subcellular Location : Nucleus (Probable).
Post-translational modifications : Phosphorylated. The phosphorylation sites are at the C-terminal part of the protein.
The N-terminus is blocked.
Similarity : Contains 1 HTH La-type RNA-binding domain.
Contains 1 RRM (RNA recognition motif) domain.
Database links : UniProtKB/Swiss-Prot: P05455.2
同SSA,广泛应用于各种自身免疫性疾病检测.
干燥症SSB/La抗体使用说明书具有全、新、优、品、好四大特点:
全:公司提供上万种产品,涵盖了生物试剂,elisa试剂盒,标准品,培养基,原装耗材,抗体、培养基、ATCC细胞等,基本上各种科研所需产品在我司都能找到。
新:产品更新速度较快,基本上每周都有新产品出现。
优:产品质量好,投诉比较少。
好:我公司具有优质的技术团队,产品一旦售出,实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。
我们提供的标记服务,可根据您科研的需求,满足您的需要,质量保证,价格合理。
一、标记流程
委托标记服务,请下载并详细填写《委托标记申请单》,待我公司标记室技术人员研究、确认后答复,并办理委托标记事宜。
二、各种标记物制备的收费标准(RMB)
我们不但提供抗体和大分子蛋白的标记服务,还提供小分子多肽及小分子蛋白的各种标记服务,提供标记化合物的服务(此化合物必须适用于标记),价格另议。
一抗和二坑的区别:
第一抗体就是平常所说的抗体,即能和抗原特异性结合。
第二抗体是能和抗体结合的,即抗体的抗体。主要用于检测抗体的存在。
一抗是针对抗原的抗体,二抗是针对一抗的抗体。即抗体也可以充当抗原刺激机体产生抗体。也就是说,抗原进入机体刺激机体免疫系统产生免疫应答,由B细胞可以产生与相应抗原发生特异性结合的特殊蛋白质。
一抗二抗都是一种可以特异结合别的物质的基团,而且一抗可以至少结合两种其他基团(底物和二抗)。
一抗:可以特异结合底物,就是识别出我们想要检测的东西。一抗和底物结合与否用肉眼是看不出来的。
二抗:可以和一抗结合,并带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团),作用是检测一抗。 如果一抗自己带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团),则不需要二抗。但这样成本很高,因为一种一抗只识别一种底物。所以如今的设计一般是二抗带上可检测标记,再来检测一抗。而一抗识别底物。这样,当一抗结合到底物上,就可以通过二抗检测出来。
Anti-SCG3/SgIII /FITC 荧光素标记分泌粒蛋白Ⅲ抗体IgGMulti-class antibodies规格: 0.2ml
rDen-2(rh-Dengue Virus) 重组人登革热病毒2型诊断抗原Multi-class antibodies规格: 100ug
鼠抗人血清白蛋白单克隆抗体 Anti-Mouse anti-human HAS 0.1ml
SREBP-1 英文名称: 胆固醇调节元件结合蛋白1抗体 0.1ml
FASN 英文名称: 脂肪酸合成酶抗体 0.1ml
Rhesus antibody Rh Phospho-PDGF Receptor beta (Tyr771) 化血小板源性生长因子受体-B抗体 规格 0.1ml
rDen-2(rh-Dengue Virus) 重组人登革热病毒2型诊断抗原Multi-class antibodies规格: 100ug
ING1/p33(inhibitor of growth gene 1) 生长抑制因子基因1抗原Multi-class antibodies规格: 0.5mg
Anti-ADFP 脂肪组织分化相关蛋白抗体Multi-class antibodies规格: 0.1ml
Rhesus antibody Rh phospho-Cdc25B (Ser186) 化细胞分裂周期蛋白25B抗体 规格 0.1ml
品名 规格 备注
Wnt3a 英文名称: 信号通路Wnt3a抗体 0.1ml
DMWD 英文名称: 强直性肌营养不良相关蛋白9抗体 0.2ml
Anti-ADFP 脂肪组织分化相关蛋白抗体Multi-class antibodies规格: 0.1ml
Substance P 英文名称: P物质抗体 0.1ml
EIF5 英文名称: 真核翻译起始因子5抗体 0.2ml
CD38抗体(人) Anti-CD38 0.1ml
Anti-VEGF-B/FITC 荧光素标记血管内皮生长因子B抗体IgGMulti-class antibodies规格: 0.2ml
Rhesus antibody Rh phospho-Gria2 (Ser880) 化谷酸受体2抗体 规格 0.1ml
CD82/KAI1 peptide 转移抑制蛋白1抗原Multi-class antibodies规格: 0.5mg
RORET, also known as RING finger protein 15 (RNF15) or zinc finger protein RoRet, is a 465 amino acid member of the TRIM family, also known as the RING-B-box coiled-coil (RBCC) family. Members of the RBCC family have an N-terminal RING finger, followed by one or two zinc-binding domains (B-box domains), a leucine coiled-coil region and a variable C-terminal domain. Found in all eukaryotes, members of the RBCC family typically function within a larger protein complex and possess ubiquitin-protein isopeptide ligase activity.
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified.
Tissue Specificity : Ubiquitous.
Similarity : Contains 1 B box-type zinc finger.
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.
Database links : UniProtKB/Swiss-Prot: O00635.1
Anti-Phospho-PKR (Thr451) /FITC 荧光素标记化蛋白激酶R抗体IgGMulti-class antibodies规格: 0.2ml
Monkey IgM (亲和纯化) 猴IgMMulti-class antibodies规格: 1mg
抗标签DYKDDDDK Tag抗体 anti-DYKDDDDK Tag /Flag-Tag polyclonal antibody 0.2ml
Rabbit Anti-Goat IgM 兔抗羊IgM 1mg
Frataxin 英文名称: 线粒体型共济失调蛋白抗体 0.2ml
Rhesus antibody Rh Phospho-RhoA(Ser188) 化RhoA蛋白抗体 规格 0.1ml
Monkey IgM (亲和纯化) 猴IgMMulti-class antibodies规格: 1mg
干燥症SSB/La抗体使用说明书OAT-1 (Organic anion transporter 1)mouse、rat 阴离子转运蛋白-1(大、小鼠同源:人源见bs-0606P)Multi-class antibodies规格: 0.5mg
Anti-CD45/B220 白细胞共同抗原抗体Multi-class antibodies规格: 0.1ml
Rhesus antibody Rh P53(wt-p53) 抑制基因抗体(野生型P53) 规格 0.1ml
PLXDC1 Kit Human 人 TEM7 / PLXDC1 ELISA配对抗体 ELISA
TSPAN6 英文名称: 四分子交联体6抗体(四旋蛋白) 0.2ml
Cyclin M2 英文名称: 周期素M2抗体 0.2ml
Anti-CD45/B220 白细胞共同抗原抗体Multi-class antibodies规格: 0.1ml
英文名称 Anti-SSB/La
中文名称 干燥症SSB/La抗体使用说明书
别 名 SSB; Lupus La protein homolog; La ribonucleoprotein; La autoantigen homolog; Sjogren syndrome type B antigen; LA_HUMAN.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human
产品类型 一抗
研究领域 免疫学
蛋白分子量 predicted molecular weight: 47kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human SSB C-terminus
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
干燥症SSB/La抗体使用说明书产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Lupus La protein (Sjogren syndrome type B antigen) (SS-B) (La ribonucleoprotein) (La autoantigen) plays a role in the transcription of RNA polymerase III. It is most probably a transcription termination factor. Binds to the 3' termini of virtually all nascent polymerase III transcripts. It is associated with precursor forms of RNA polymerase III transcripts including tRNA and 4.5S, 5S, 7S, and 7-2 RNAs. The phosphorylation sites are at the C-terminal part of the protein. Sera from patients with systemic lupus erythematosus(SLE) often contain antibodies that react with the normal cellular La protein as if this antigen was foreign.
Function : Binds to the 3' poly(U) terminii of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.
Subunit : Interacts with DDX15. May interact with RUFY1.
Subcellular Location : Nucleus (Probable).
Post-translational modifications : Phosphorylated. The phosphorylation sites are at the C-terminal part of the protein.
The N-terminus is blocked.
Similarity : Contains 1 HTH La-type RNA-binding domain.
Contains 1 RRM (RNA recognition motif) domain.
Database links : UniProtKB/Swiss-Prot: P05455.2
同SSA,广泛应用于各种自身免疫性疾病检测.
干燥症SSB/La抗体使用说明书具有全、新、优、品、好四大特点:
全:公司提供上万种产品,涵盖了生物试剂,elisa试剂盒,标准品,培养基,原装耗材,抗体、培养基、ATCC细胞等,基本上各种科研所需产品在我司都能找到。
新:产品更新速度较快,基本上每周都有新产品出现。
优:产品质量好,投诉比较少。
好:我公司具有优质的技术团队,产品一旦售出,实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。
我们提供的标记服务,可根据您科研的需求,满足您的需要,质量保证,价格合理。
一、标记流程
委托标记服务,请下载并详细填写《委托标记申请单》,待我公司标记室技术人员研究、确认后答复,并办理委托标记事宜。
二、各种标记物制备的收费标准(RMB)
我们不但提供抗体和大分子蛋白的标记服务,还提供小分子多肽及小分子蛋白的各种标记服务,提供标记化合物的服务(此化合物必须适用于标记),价格另议。
一抗和二坑的区别:
第一抗体就是平常所说的抗体,即能和抗原特异性结合。
第二抗体是能和抗体结合的,即抗体的抗体。主要用于检测抗体的存在。
一抗是针对抗原的抗体,二抗是针对一抗的抗体。即抗体也可以充当抗原刺激机体产生抗体。也就是说,抗原进入机体刺激机体免疫系统产生免疫应答,由B细胞可以产生与相应抗原发生特异性结合的特殊蛋白质。
一抗二抗都是一种可以特异结合别的物质的基团,而且一抗可以至少结合两种其他基团(底物和二抗)。
一抗:可以特异结合底物,就是识别出我们想要检测的东西。一抗和底物结合与否用肉眼是看不出来的。
二抗:可以和一抗结合,并带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团),作用是检测一抗。 如果一抗自己带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团),则不需要二抗。但这样成本很高,因为一种一抗只识别一种底物。所以如今的设计一般是二抗带上可检测标记,再来检测一抗。而一抗识别底物。这样,当一抗结合到底物上,就可以通过二抗检测出来。
Anti-SCG3/SgIII /FITC 荧光素标记分泌粒蛋白Ⅲ抗体IgGMulti-class antibodies规格: 0.2ml
rDen-2(rh-Dengue Virus) 重组人登革热病毒2型诊断抗原Multi-class antibodies规格: 100ug
鼠抗人血清白蛋白单克隆抗体 Anti-Mouse anti-human HAS 0.1ml
SREBP-1 英文名称: 胆固醇调节元件结合蛋白1抗体 0.1ml
FASN 英文名称: 脂肪酸合成酶抗体 0.1ml
Rhesus antibody Rh Phospho-PDGF Receptor beta (Tyr771) 化血小板源性生长因子受体-B抗体 规格 0.1ml
rDen-2(rh-Dengue Virus) 重组人登革热病毒2型诊断抗原Multi-class antibodies规格: 100ug
ING1/p33(inhibitor of growth gene 1) 生长抑制因子基因1抗原Multi-class antibodies规格: 0.5mg
Anti-ADFP 脂肪组织分化相关蛋白抗体Multi-class antibodies规格: 0.1ml
Rhesus antibody Rh phospho-Cdc25B (Ser186) 化细胞分裂周期蛋白25B抗体 规格 0.1ml
品名 规格 备注
Wnt3a 英文名称: 信号通路Wnt3a抗体 0.1ml
DMWD 英文名称: 强直性肌营养不良相关蛋白9抗体 0.2ml
Anti-ADFP 脂肪组织分化相关蛋白抗体Multi-class antibodies规格: 0.1ml
Substance P 英文名称: P物质抗体 0.1ml
EIF5 英文名称: 真核翻译起始因子5抗体 0.2ml
CD38抗体(人) Anti-CD38 0.1ml
Anti-VEGF-B/FITC 荧光素标记血管内皮生长因子B抗体IgGMulti-class antibodies规格: 0.2ml
Rhesus antibody Rh phospho-Gria2 (Ser880) 化谷酸受体2抗体 规格 0.1ml
CD82/KAI1 peptide 转移抑制蛋白1抗原Multi-class antibodies规格: 0.5mg
RORET, also known as RING finger protein 15 (RNF15) or zinc finger protein RoRet, is a 465 amino acid member of the TRIM family, also known as the RING-B-box coiled-coil (RBCC) family. Members of the RBCC family have an N-terminal RING finger, followed by one or two zinc-binding domains (B-box domains), a leucine coiled-coil region and a variable C-terminal domain. Found in all eukaryotes, members of the RBCC family typically function within a larger protein complex and possess ubiquitin-protein isopeptide ligase activity.
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified.
Tissue Specificity : Ubiquitous.
Similarity : Contains 1 B box-type zinc finger.
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.
Database links : UniProtKB/Swiss-Prot: O00635.1
Anti-Phospho-PKR (Thr451) /FITC 荧光素标记化蛋白激酶R抗体IgGMulti-class antibodies规格: 0.2ml
Monkey IgM (亲和纯化) 猴IgMMulti-class antibodies规格: 1mg
抗标签DYKDDDDK Tag抗体 anti-DYKDDDDK Tag /Flag-Tag polyclonal antibody 0.2ml
Rabbit Anti-Goat IgM 兔抗羊IgM 1mg
Frataxin 英文名称: 线粒体型共济失调蛋白抗体 0.2ml
Rhesus antibody Rh Phospho-RhoA(Ser188) 化RhoA蛋白抗体 规格 0.1ml
Monkey IgM (亲和纯化) 猴IgMMulti-class antibodies规格: 1mg
干燥症SSB/La抗体使用说明书OAT-1 (Organic anion transporter 1)mouse、rat 阴离子转运蛋白-1(大、小鼠同源:人源见bs-0606P)Multi-class antibodies规格: 0.5mg
Anti-CD45/B220 白细胞共同抗原抗体Multi-class antibodies规格: 0.1ml
Rhesus antibody Rh P53(wt-p53) 抑制基因抗体(野生型P53) 规格 0.1ml
PLXDC1 Kit Human 人 TEM7 / PLXDC1 ELISA配对抗体 ELISA
TSPAN6 英文名称: 四分子交联体6抗体(四旋蛋白) 0.2ml
Cyclin M2 英文名称: 周期素M2抗体 0.2ml
Anti-CD45/B220 白细胞共同抗原抗体Multi-class antibodies规格: 0.1ml
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干燥症SSB/La抗体使用说明书
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