重组人羧肽酶B2(CPB2)

特别提示：包括重组人羧肽酶B2(CPB2)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人羧肽酶B2(CPB2)
英文名称：Recombinant Human Carboxypeptidase B2
产品货号：JN1741
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Phe23-Val423在C端含有His标签。

CPB2质量控制：＞95%(还原性SDS-PAGE)

CPB2制剂：液体

CPB2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于CPB2：
Carboxypeptidase B2 (CPB2) is a secreted enzyme that belongs to the peptidase M14 family. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen by the liver and circulates in the plasma as a plasminogen-bound zymogen. CPB2 cleaves C-terminal arginine or lysine residues from biologically active peptides, such as kinins or anaphylatoxins, in the circulation regulating their activities. CPB2 also down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. CPB2 exhibits carboxypeptidase activity when it is activated by proteolysis at residue Arg92 of the thrombin/thrombomodulin complex. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.

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