Deoxynucleotidyltransferase terminal; DNA nucleotidylexotransferase; DNTT; Nucleosidetriphosphate DNA deoxynucleotidylexotransferase; Terminal addition enzyme; Terminal deoxynucleotidyltransferase; Terminal deoxyribonucleotidyltransferase; Terminal transferase; TDT_HUMAN.
规格价格
100ul/2980元 购买 大包装/询价
说 明 书
100ul
研究领域
细胞生物 免疫学 染色质和核信号
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Mouse, Rat, Dog, Horse, Rabbit,
产品应用
IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
58kDa
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human TdT/DNTT
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍
background: TdT is a nuclear enzyme involved in the recombination of Immunoglobulin and T cell receptor genes. It is expressed in early lymphoid cells and by tumour cells in certain classes of acute lymphoid leukaemia.
Subunit: Interacts with PRP19 and DNTTIP1. Forms a ternary complex with DNTTIP2 and core histone. Released from this complex by PCNA.
Subcellular Location: Nucleus.
Similarity: Belongs to the DNA polymerase type-X family. Contains 1 BRCT domain.
Database links:
Entrez Gene: 1791 Human
Entrez Gene: 21673 Mouse
Entrez Gene: 294051 Rat
Omim: 187410 Human
SwissProt: P04053 Human
SwissProt: P09838 Mouse
Unigene: 534206 Human
Unigene: 25620 Mouse
Unigene: 143741 Rat
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.