Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Fruit Fly, Zebrafish
适应物种:
Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Fruit Fly, Zebrafish
免疫原:
详见说明书
亚型:
IGg
形态:
粉末、液体、冻干粉
应用范围:
详见说明书
浓度:
1mg/ml
保存条件:
-20 °C
规格:
100ul
FITC标记的沉默调节相关蛋白4抗体
英文名称
Anti-SIRT4/FITC
中文名称
FITC标记的沉默调节相关蛋白4抗体
别 名
NAD dependent deacetylase sirtuin 4; NAD-dependent ADP-ribosyltransferase sirtuin-4; Silent mating type information regulation 2 homolog; Sir 2 like 4; SIR 2 like protein 4; Sir2 like 4; SIR2 like protein 4; SIR2-like protein 4; SIR2L 4; SIR2L4; SIRT 4; Sirt4; SIRT4_HUMAN; Sirtuin (silent mating type information regulation 2 homolog) 4; Sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae); Sirtuin 4; Sirtuin type 4; Sirtuin4.
规格价格
100ul/2980元 购买 大包装/询价
说 明 书
100ul
研究领域
心血管 细胞生物 信号转导 糖尿病 表观遗传学
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Fruit Fly, Zebrafish
产品应用
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
32kDa
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human SIRT4/SIR 2 like protein 4
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍
background: NAD-dependent protein ADP-ribosyl transferase. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1. Inhibits GLUD1 enzyme activity. Down-regulates insulin secretion. Has no detectable protein deacetylase activity.
Function: NAD-dependent protein ADP-ribosyl transferase. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1. Inhibits GLUD1 enzyme activity. Down-regulates insulin secretion. Has no detectable protein deacetylase activity.
Subunit: Interacts with GLUD1, IDE and SLC25A5.
Subcellular Location: Mitochondrion matrix.
Tissue Specificity: Detected in vascular smooth muscle and striated muscle. Detected in insulin-producing beta-cells in pancreas islets of Langerhans (at protein level). Widely expressed. Weakly expressed in leukocytes and fetal thymus.
Similarity: Belongs to the sirtuin family. Class II subfamily. Contains 1 deacetylase sirtuin-type domain.
Database links:
Entrez Gene: 519328 Cow
Entrez Gene: 23409 Human
Entrez Gene: 75387 Mouse
Entrez Gene: 100125349 Pig
Entrez Gene: 304539 Rat
Omim: 604482 Human
SwissProt: Q1JQC6 Cow
SwissProt: Q9Y6E7 Human
SwissProt: Q8R216 Mouse
Unigene: 50861 Human
Unigene: 332616 Mouse
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.