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- 详细信息
- 文献和实验
- 技术资料
- 库存:
420
- 英文名:
Recombinant Human Fructose-Bisphosphate Aldolase A
- 保质期:
6个月
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
收到货后请置于-20℃
- 规格:
10μg|50μg|500μg|1mg
特别提示:包括重组人果糖二磷酸醛缩酶A(ALDOA)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人果糖二磷酸醛缩酶A(ALDOA)
英文名称:Recombinant Human Fructose-Bisphosphate Aldolase A
产品货号:JN1977
产品规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Pro2-Tyr364在C端含有His标签。
ALDOA质量控制:>95%(还原性SDS-PAGE)
ALDOA制剂:液体
ALDOA保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于ALDOA:
Fructose Bisphosphate Aldolase A (ALDOA) belongs to the class I fructose-bisphosphate aldolase family. ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. In vertebrates, three forms of this ubiquitous glycolytic enzyme are found, Aldolase A in muscle, Aldolase B in liver and aldolase C in brain. Aldolase A Interacts with SNX9 and WAS. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. In addition, Aldolase A plays an important role in glycolysis and gluconeogenesis; it may also act as a scaffolding protein.
除了重组人果糖二磷酸醛缩酶A(ALDOA),,我公司还供应以下相关产品:
名称:重组人趋化因子CCL26(Eotaxin-3)
货号:JN0305
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Thr24-Leu94表达纯化而来。
CCL26/Eotaxin-3质量控制:>95%(还原性SDS-PAGE)。
CCL26/Eotaxin-3制剂:液体
CCL26/Eotaxin-3保存:
收到后请置于-20℃,可稳定保存6个月,避免反复冻融。
关于CCL26/Eotaxin-3:
Chemokine Ligand 26 protein (CCL26) is a novel small cytokine belonging to the CC chemokine family which is involved in immunoregulatory and inflammatory processes. CCL26 is constitutively expressed in thymus, but only transiently expressed in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL26, along with Eotaxin-1 and Eotaxin-2, selectively activates the CC chemokine receptor 3 (CCR3). The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma. The full-length cDNA for CCL26 encodes a protein of 94 amino acids with a putative signal peptide of either 23 or 26 amino acid residues. Both the 71 and 68 amino acid residue variants of recombinant CCL26 demonstrate equal potency in inducing chemotaxis of a human CCR3-transfected cell line. Unlike most other CC chemokines, CCL26 maps to human chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. CCL26 and Eotaxin-2 are unique in that they are the only chemokines identified to date that map to chromosome 7.
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文献和实验磷酸化,转变为1,6-果糖二磷酸,由6磷酸果糖激酶催化,消耗1分子ATP,是第二个不可逆的磷酸化反应,酵解过程关键步骤之二,是葡萄糖氧化过程中最重要的调节点。 第二阶段是裂解阶段。1,6-果糖二磷酸折半分解成2分子磷酸丙糖(磷酸二羟丙酮和3-磷酸甘油醛),醛缩酶催化,二者可互变,最终1分子葡萄糖转变为2分子3-磷酸甘油醛。 …… 点击查看更多:bbs.med66.com/forum-267-250/topic-1669831.html
临床医学检验技术资格考试考点精要(临床化学检验) 1. 糖酵解:葡萄糖至乳糖。葡萄糖→葡萄糖6磷酸(已糖激酶,不可逆,1ATP)→果糖6磷酸(磷酸已糖异构酶)→1,6果糖二磷酸(6磷酸果糖激酶,最重要点,不可逆,1ATP)→磷酸丙糖(醛缩酶,可逆)→3磷酸甘油醛→磷酸烯醇式丙酮酸→(经丙酮酸激酶)→烯醇式丙酮酸和ATP(不可逆)。可生成2分子ATP. …… 点击查看更多:http://bbs.med66.com/forum-267-250
磷酸化,转变为由6磷酸果糖激酶催化,消耗1分子ATP,是第二个不可逆的磷酸化反应,酵解过程关键步骤之二,是葡萄糖氧化过程中最重要的调节点。 (2)第二阶段:裂解阶段。1,6-果糖二磷酸折半分解成2分子磷酸丙糖(磷酸二羟丙酮和3-磷酸甘油醛),醛缩酶催化,二者可互变,最终1分子葡萄糖转变为2分子3-磷酸甘油醛。 (3)第三阶段:通过氧化还原生成乳酸。(能量的释放和保留) ①3-磷酸甘油醛的氧化和NAD+的还原,由3-磷酸甘油醛脱氢酶催化,生成1,3-二磷酸甘油酸,产生一个高能磷酸键
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