Human, Mouse, Rat, Dog, Cow, Fruit Fly, ,SheepDog,Zebrafish
适应物种:
Human, Mouse, Rat, Dog, Cow, Fruit Fly, ,SheepDog,Zebrafish
免疫原:
详见说明书
亚型:
IGg
形态:
粉末、液体、冻干粉
应用范围:
IF=1:50-200
浓度:
1mg/ml
保存条件:
-20 °C
规格:
100ul
FITC标记的酸性核磷蛋白32家族B抗体
英文名称
Anti-PHAPI2/FITC
中文名称
FITC标记的酸性核磷蛋白32家族B抗体
别 名
Acidic (leucine rich) nuclear phosphoprotein 32 family member B; Acidic leucine rich nuclear phosphoprotein 32 family member B; Acidic leucine-rich nuclear phosphoprotein 32 family member B; Acidic nuclear phosphoprotein 32 family member B; Acidic protein rich in leucines; AN32B_HUMAN; ANP 32B; ANP32B; APRIL; PAL 31; PAL31; PHAPI 2; PHAPI2; PHAPI2 protein; PHAPI2a; Proliferation related acidic leucine rich protein; Putative HLA-DR-associated protein I-2; Silver stainable protein SSP 29; Silver stainable protein SSP29; Silver-stainable protein SSP29; Ssp 29; Ssp29.
规格价格
100ul/2980元 购买 大包装/询价
说 明 书
100ul
研究领域
细胞生物 信号转导 细胞凋亡 细胞周期蛋白 转录调节因子
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Mouse, Rat, Dog, Cow, Fruit Fly, ,SheepDog,Zebrafish
产品应用
IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
29kDa
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from hu PHAPI2/APRIL
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍
background: Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.
Function: Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.
Subunit: Monomer. Interacts with histones H3 and H4.
Subcellular Location: Isoform 1: Nucleus. Note=Accumulates in the nuclei at the S phase (By similarity). Isoform 2: Cytoplasm. Note=Lacks a nuclear localization signal.
Tissue Specificity: Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.
Post-translational modifications: Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group (By similarity).
Similarity: Belongs to the ANP32 family. Contains 4 LRR (leucine-rich) repeats. Contains 1 LRRCT domain.
Database links:
Entrez Gene: 10541 Human
Entrez Gene: 67628 Mouse
Entrez Gene: 170724 Rat
SwissProt: Q92688 Human
SwissProt: Q9EST5 Mouse
SwissProt: Q9EST6 Rat
Unigene: 494604 Human
Unigene: 263913 Mouse
Unigene: 20465 Rat
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.