LS-F50690 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the Quantitative detection of Human CYPOR / POR. It is based upon a Custom assay principle.
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Specifications
Type
Custom ELISA kit
All LSBio Custom kits have been predesigned and all necessary components, including antibodies and standards have been identified. Upon receiving a custom kit order, the kit will be assembled and quality control tested before being shipped out. Kit assembly and testing typically takes 4 to 6 weeks. In most cases the final kit is based on the Sandwich assay principle, with a few being Competitive EIA based. Specifications such as Range, Sensitivity, and Precision are defined upon completion. In the event that the custom kit cannot be successfully developed with 6 weeks of the order date, the customer will be notified and the order canceled at no cost.
Target
CYPOR / POR
Synonyms
POR, CPR, CYPOR, p450R
Reactivity
Human
Manual
Format
96-Well Microplate
Detection
Colorimetric - 450nm (TMB)
Measurement
Quantitative
Detection Range
To be determined
Sensitivity
To be determined
Assay Time
4.5 h
Precision
Intra-Assay: CV<10% / Inter-Assay: CV<12%
Storage
Store at 4°C for 6 months or at -20°C for 1 year. Avoid freeze/thaw cycles.
Kit Components
CYPOR / POR is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. P16435AB051763BAB18572.1