Cytokinesis and spindle organization B; NSP 5 alpha 3 alpha; Cytospin B; FLJ36955; HCMOGT 1; NSP; NSP5; Nuclear structure protein 5; SPECC1; Spectrin domain with coiled coils 1; Sperm antigen HCMOGT 1; Sperm antigen with calponin homology and coiled coil domains 1; Structure protein NSP5a3a; Structure protein NSP5a3b; Structure protein NSP5b3a; Structure protein NSP5b3b; CYTSB_HUMAN.
规格价格
100ul/2980元 购买 大包装/询价
说 明 书
100ul
研究领域
肿瘤 细胞生物 细胞周期蛋白 细胞类型标志物
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Rat, Dog, Rabbit, Sheep,
产品应用
IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
119kDa
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human NSP5
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍
background: NSP type 5 alpha 3 alpha is a novel structure protein belonging to the cytospin-A family, that may play a role in nuclear function during cell division. It is also highly expressed in certain tumor cell lines, suggesting that it may serve as a good tumor marker. It was was cloned as part of a chromosomal translocation involving PDGFRB in a case of juvenile myelomonocytic leukemia.
Subcellular Location: Nucleus.
Tissue Specificity: Highly expressed in testis. Barely detectablein other tissues. Also highly expressed in some cancer cell lines.
DISEASE: Note=A chromosomal aberration involving CYTSB may be acause of juvenile myelomonocytic leukemia. Translocationt(5;17)(q33;p11.2) with PDGFRB.
Similarity: Belongs to the cytospin-A family. Contains 1 CH (calponin-homology) domain.
Database links:
Entrez Gene: 92521 Human
Omim: 608793 Human
SwissProt: Q5M775 Human
Unigene: 431045 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.