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- 详细信息
- 技术资料
- 抗体名:
蛋白质磷酸酶2A-B55抗体价格
- 抗体英文名:
Anti-PPP2R2B/PP2A-B55
- 靶点:
详见说明书
- 浓度:
1mg/1ml
- 应用范围:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
- 宿主:
详见说明书
- 供应商:
上海博湖
- 库存:
大量
- 级别:
详见说明书
- 目录编号:
详见说明书
- 抗原来源:
Rabbit
- 保质期:
详见说明书
- 适应物种:
详见说明书
- 标记物:
详见说明书
- 克隆性:
多克隆
- 保存条件:
Store at -20 °C
- 形态:
大量
- 亚型:
IgG
- 免疫原:
KLH conjugated synthetic peptide derived from human PPP2R2B/PP2A-B55 (51-130aa)
- 规格:
0.2ml/200μg
中文名称 蛋白质磷酸酶2A-B55抗体价格
英文名称 Anti-PPP2R2B/PP2A-B55
别 名 2ABB_HUMAN; B55 beta; Beta isoform of regulatory subunit B55 protein phosphatase 2; MGC24888; PP2A B Subunit B Alpha Isoform; PP2A B55beta; PP2A PR55B; PP2A subunit B B beta isoform; PP2A subunit B B55 beta isoform; PP2A subunit B isoform B55 beta; PP2A subunit B isoform B55-beta; PP2A subunit B isoform beta; PP2A subunit B isoform PR55 beta; PP2A subunit B isoform PR55-beta; PP2A subunit B isoform R2 beta; PP2A subunit B isoform R2-beta; PP2A subunit B PR55 beta isoform; PP2A subunit B R2 beta isoform; Ppp2r2b; PR2AB beta; PR2AB55 beta; PR2APR55 beta; PR52B; PR55 beta; Protein phosphatase 2 (formerly 2A) regulatory subunit B (PR 52) beta isoform; Protein phosphatase 2 (formerly 2A) regulatory subunit B beta isoform; Protein phosphatase 2 regulatory subunit B; Protein phosphatase 2 regulatory subunit B beta isoform; SCA 12; SCA12; Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; Serine/Threonine Protein Phosphatase 2A 56kDa Regulatory Subunit Alpha Isoform; Serine/threonine protein phosphatase 2A neuronal isoform; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform.
蛋白质磷酸酶2A-B55抗体价格是用于化学反应、分析化验、研究实验、教学实验、化学配方使用的纯净化学品,产品品质卓越,价格实惠,多种规格供应,售后完善。
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Rabbit, Sheep
产品类型 一抗
研究领域 细胞生物 神经生物学 信号转导 激酶和磷酸酶
蛋白分子量 predicted molecular weight: 52kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human PPP2R2B/PP2A-B55 (51-130aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
蛋白质磷酸酶2A-B55抗体价格产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2Aå and PP2A∫. The PP2A catalytic subunit associates with a variety of regulatory subunits. The B family of regulatory subunits (including B55, B56 and PR72/130 subfamilies) is believed to participate in substrate specificity and catalytic activity. PP2A-B55, also known as PP2A regulatory subunit subfamily B55 or PP2A-B1, is a B subfamily consisting of four B55 isoforms (Alpha,Beta, Gamma and Delta) encoded by four distinct genes.
Function : The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance.
Subunit : PP2A consists of a common heterodimeric core enzyme,composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDaconstant regulatory subunit (PR65 or subunit A), that associateswith a variety of regulatory subunits. Proteins that associate withthe core dimer include three families of regulatory subunits B (theR2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the48 kDa variable regulatory subunit, viral proteins, and cellsignaling molecules.
Subcellular Location : Cytoplasm. cytoskeleton. Membrane and Cytoplasm. Mitochondrion. Mitochondrion outer membrane. Under basal conditions, localizes to both cytosolic and mitochondrial compartments. Relocalizes from the cytosolic to the mitochondrial compartment during apoptosis. Its targeting to the outer mitochondrial membrane (OMM) involves an association with import receptors of the TOM complex and is required to promote proapoptotic activity.
DISEASE : Defects in PPP2R2B are the cause of spinocerebellar ataxia type 12 (SCA12) [MIM:604326]. Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA12 is an autosomal dominant cerebellar ataxia (ADCA).
Similarity : Belongs to the phosphatase 2A regulatory subunit B family.
Contains 7 WD repeats.
Database links : UniProtKB/Swiss-Prot: Q00005.1
蛋白质磷酸酶2A-B55抗体价格具有全、新、优、品、好四大特点:
全:公司提供上万种产品,涵盖了生物试剂,elisa试剂盒,标准品,培养基,原装耗材,抗体、培养基、ATCC细胞等,基本上各种科研所需产品在我司都能找到。
新:产品更新速度较快,基本上每周都有新产品出现。
优:产品质量好,投诉比较少。
好:我公司具有优质的技术团队,产品一旦售出,实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。
我们提供的标记服务,可根据您科研的需求,满足您的需要,质量保证,价格合理。
一、标记流程
委托标记服务,请下载并详细填写《委托标记申请单》,待我公司标记室技术人员研究、确认后答复,并办理委托标记事宜。
二、各种标记物制备的收费标准(RMB)
我们不但提供抗体和大分子蛋白的标记服务,还提供小分子多肽及小分子蛋白的各种标记服务,提供标记化合物的服务(此化合物必须适用于标记),价格另议。
一抗和二坑的区别:
第一抗体就是平常所说的抗体,即能和抗原特异性结合。
第二抗体是能和抗体结合的,即抗体的抗体。主要用于检测抗体的存在。
一抗是针对抗原的抗体,二抗是针对一抗的抗体。即抗体也可以充当抗原刺激机体产生抗体。也就是说,抗原进入机体刺激机体免疫系统产生免疫应答,由B细胞可以产生与相应抗原发生特异性结合的特殊蛋白质。
一抗二抗都是一种可以特异结合别的物质的基团,而且一抗可以至少结合两种其他基团(底物和二抗)。
一抗:可以特异结合底物,就是识别出我们想要检测的东西。一抗和底物结合与否用肉眼是看不出来的。
二抗:可以和一抗结合,并带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团),作用是检测一抗。 如果一抗自己带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团),则不需要二抗。但这样成本很高,因为一种一抗只识别一种底物。所以如今的设计一般是二抗带上可检测标记,再来检测一抗。而一抗识别底物。这样,当一抗结合到底物上,就可以通过二抗检测出来。
01群小川型霍乱弧菌抗体 Anti-V.cholera Ogawa WB IHC-P IHC-F IF 100ul
囊泡相关膜蛋白1,2,3抗体 Anti-VAMP-1+2+3 WB IHC-P IHC-F IF 100ul
神经内分泌调节肽VGF抗体 Anti-VGF/NERP2 WB IHC-P IHC-F IF 100ul
重组猪细小病毒VP2蛋白抗体 Anti-VP2 WB IHC-P IHC-F IF 100ul
血管内皮生长因子D型抗体 Anti-VEGF-D WB
周期素依赖性激酶5调节蛋白1样蛋白1抗体 Anti-CDKAL1 WB IHC-P IHC-F IF 100ul
22号染色体开放阅读框31抗体 Anti-C22orf31 WB IHC-P IHC-F IF 100ul
细胞分裂周期37样蛋白1抗体 Anti-CDC37L1 WB IHC-P IHC-F IF 100ul
羧肽酶X抗体 Anti-CPXM WB IHC-P IHC-F IF 100ul
卷曲螺旋结构域蛋白135抗体 Anti-CCDC135 WB IHC-P IHC-F IF 100ul
泛素结合蛋白P62抗体 Anti-SQSTM1 WB IHC-P IHC-F IF 100ul
Rap2A抗体 Anti-Rap2A WB IHC-P IHC-F IF 100ul
胰岛β细胞生长因子Reg IIIγ抗体 Anti-Reg3 gamma WB IHC-P IHC-F IF 100ul
胰岛β细胞生长因子Reg IIIα 抗体 Anti-Reg3 beta WB IHC-P IHC-F IF 100ul
核糖体蛋白S6修饰样蛋白A抗体 Anti-RIMKLA WB IHC-P IHC-F IF 100ul
可溶性淀粉培养基250g用于微生物的淀粉水解试验
25300-062 500ml incubation media 25300-062 500ml
黄绿青霉 腐乳。 支/瓶
山梨醇麦康凯琼脂(SMAC)平板(9cm)用于大肠杆菌O离培养
SabouraudDextroseAgar
维生素K加入HB0398中
纤维二糖-多粘菌素E(CC)琼脂 用于创伤弧菌分离培养基
Lambda Broth Lambda Broth 100克 BR
酵母膏-麦芽膏琼脂ISPMedium2(YeastExtractMaltExtractAgar)250g/瓶用于链霉菌属的培养鉴定incubationmedia酵母膏-麦芽膏琼脂ISPMedium2(YeastExtractMaltExtractAgar)250g/瓶用于链霉菌属的培养鉴定
大肠杆菌显色培养基 1000ml 用于快速、准确检测大肠杆菌,培
蛋白质磷酸酶2A-B55抗体价格细菌蛋白胨 250g 用于制备0.1%蛋白胨水,用于空肠弯曲菌的预增菌
明胶盐缓冲液 250g 用于检测肉毒梭菌时样品稀释液
ModifiedSclohtens'Broth(MSB) 250g 用于阴沟肠杆菌的培养
含1%棉籽糖的PY培养基 1ml*20支 用于产气荚膜梭菌生化试验
英文名称 Anti-PPP2R2B/PP2A-B55
别 名 2ABB_HUMAN; B55 beta; Beta isoform of regulatory subunit B55 protein phosphatase 2; MGC24888; PP2A B Subunit B Alpha Isoform; PP2A B55beta; PP2A PR55B; PP2A subunit B B beta isoform; PP2A subunit B B55 beta isoform; PP2A subunit B isoform B55 beta; PP2A subunit B isoform B55-beta; PP2A subunit B isoform beta; PP2A subunit B isoform PR55 beta; PP2A subunit B isoform PR55-beta; PP2A subunit B isoform R2 beta; PP2A subunit B isoform R2-beta; PP2A subunit B PR55 beta isoform; PP2A subunit B R2 beta isoform; Ppp2r2b; PR2AB beta; PR2AB55 beta; PR2APR55 beta; PR52B; PR55 beta; Protein phosphatase 2 (formerly 2A) regulatory subunit B (PR 52) beta isoform; Protein phosphatase 2 (formerly 2A) regulatory subunit B beta isoform; Protein phosphatase 2 regulatory subunit B; Protein phosphatase 2 regulatory subunit B beta isoform; SCA 12; SCA12; Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; Serine/Threonine Protein Phosphatase 2A 56kDa Regulatory Subunit Alpha Isoform; Serine/threonine protein phosphatase 2A neuronal isoform; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform.
蛋白质磷酸酶2A-B55抗体价格是用于化学反应、分析化验、研究实验、教学实验、化学配方使用的纯净化学品,产品品质卓越,价格实惠,多种规格供应,售后完善。
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Rabbit, Sheep
产品类型 一抗
研究领域 细胞生物 神经生物学 信号转导 激酶和磷酸酶
蛋白分子量 predicted molecular weight: 52kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human PPP2R2B/PP2A-B55 (51-130aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
蛋白质磷酸酶2A-B55抗体价格产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2Aå and PP2A∫. The PP2A catalytic subunit associates with a variety of regulatory subunits. The B family of regulatory subunits (including B55, B56 and PR72/130 subfamilies) is believed to participate in substrate specificity and catalytic activity. PP2A-B55, also known as PP2A regulatory subunit subfamily B55 or PP2A-B1, is a B subfamily consisting of four B55 isoforms (Alpha,Beta, Gamma and Delta) encoded by four distinct genes.
Function : The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance.
Subunit : PP2A consists of a common heterodimeric core enzyme,composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDaconstant regulatory subunit (PR65 or subunit A), that associateswith a variety of regulatory subunits. Proteins that associate withthe core dimer include three families of regulatory subunits B (theR2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the48 kDa variable regulatory subunit, viral proteins, and cellsignaling molecules.
Subcellular Location : Cytoplasm. cytoskeleton. Membrane and Cytoplasm. Mitochondrion. Mitochondrion outer membrane. Under basal conditions, localizes to both cytosolic and mitochondrial compartments. Relocalizes from the cytosolic to the mitochondrial compartment during apoptosis. Its targeting to the outer mitochondrial membrane (OMM) involves an association with import receptors of the TOM complex and is required to promote proapoptotic activity.
DISEASE : Defects in PPP2R2B are the cause of spinocerebellar ataxia type 12 (SCA12) [MIM:604326]. Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA12 is an autosomal dominant cerebellar ataxia (ADCA).
Similarity : Belongs to the phosphatase 2A regulatory subunit B family.
Contains 7 WD repeats.
Database links : UniProtKB/Swiss-Prot: Q00005.1
蛋白质磷酸酶2A-B55抗体价格具有全、新、优、品、好四大特点:
全:公司提供上万种产品,涵盖了生物试剂,elisa试剂盒,标准品,培养基,原装耗材,抗体、培养基、ATCC细胞等,基本上各种科研所需产品在我司都能找到。
新:产品更新速度较快,基本上每周都有新产品出现。
优:产品质量好,投诉比较少。
好:我公司具有优质的技术团队,产品一旦售出,实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。
我们提供的标记服务,可根据您科研的需求,满足您的需要,质量保证,价格合理。
一、标记流程
委托标记服务,请下载并详细填写《委托标记申请单》,待我公司标记室技术人员研究、确认后答复,并办理委托标记事宜。
二、各种标记物制备的收费标准(RMB)
我们不但提供抗体和大分子蛋白的标记服务,还提供小分子多肽及小分子蛋白的各种标记服务,提供标记化合物的服务(此化合物必须适用于标记),价格另议。
一抗和二坑的区别:
第一抗体就是平常所说的抗体,即能和抗原特异性结合。
第二抗体是能和抗体结合的,即抗体的抗体。主要用于检测抗体的存在。
一抗是针对抗原的抗体,二抗是针对一抗的抗体。即抗体也可以充当抗原刺激机体产生抗体。也就是说,抗原进入机体刺激机体免疫系统产生免疫应答,由B细胞可以产生与相应抗原发生特异性结合的特殊蛋白质。
一抗二抗都是一种可以特异结合别的物质的基团,而且一抗可以至少结合两种其他基团(底物和二抗)。
一抗:可以特异结合底物,就是识别出我们想要检测的东西。一抗和底物结合与否用肉眼是看不出来的。
二抗:可以和一抗结合,并带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团),作用是检测一抗。 如果一抗自己带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团),则不需要二抗。但这样成本很高,因为一种一抗只识别一种底物。所以如今的设计一般是二抗带上可检测标记,再来检测一抗。而一抗识别底物。这样,当一抗结合到底物上,就可以通过二抗检测出来。
01群小川型霍乱弧菌抗体 Anti-V.cholera Ogawa WB IHC-P IHC-F IF 100ul
囊泡相关膜蛋白1,2,3抗体 Anti-VAMP-1+2+3 WB IHC-P IHC-F IF 100ul
神经内分泌调节肽VGF抗体 Anti-VGF/NERP2 WB IHC-P IHC-F IF 100ul
重组猪细小病毒VP2蛋白抗体 Anti-VP2 WB IHC-P IHC-F IF 100ul
血管内皮生长因子D型抗体 Anti-VEGF-D WB
周期素依赖性激酶5调节蛋白1样蛋白1抗体 Anti-CDKAL1 WB IHC-P IHC-F IF 100ul
22号染色体开放阅读框31抗体 Anti-C22orf31 WB IHC-P IHC-F IF 100ul
细胞分裂周期37样蛋白1抗体 Anti-CDC37L1 WB IHC-P IHC-F IF 100ul
羧肽酶X抗体 Anti-CPXM WB IHC-P IHC-F IF 100ul
卷曲螺旋结构域蛋白135抗体 Anti-CCDC135 WB IHC-P IHC-F IF 100ul
泛素结合蛋白P62抗体 Anti-SQSTM1 WB IHC-P IHC-F IF 100ul
Rap2A抗体 Anti-Rap2A WB IHC-P IHC-F IF 100ul
胰岛β细胞生长因子Reg IIIγ抗体 Anti-Reg3 gamma WB IHC-P IHC-F IF 100ul
胰岛β细胞生长因子Reg IIIα 抗体 Anti-Reg3 beta WB IHC-P IHC-F IF 100ul
核糖体蛋白S6修饰样蛋白A抗体 Anti-RIMKLA WB IHC-P IHC-F IF 100ul
可溶性淀粉培养基250g用于微生物的淀粉水解试验
25300-062 500ml incubation media 25300-062 500ml
黄绿青霉 腐乳。 支/瓶
山梨醇麦康凯琼脂(SMAC)平板(9cm)用于大肠杆菌O离培养
SabouraudDextroseAgar
维生素K加入HB0398中
纤维二糖-多粘菌素E(CC)琼脂 用于创伤弧菌分离培养基
Lambda Broth Lambda Broth 100克 BR
酵母膏-麦芽膏琼脂ISPMedium2(YeastExtractMaltExtractAgar)250g/瓶用于链霉菌属的培养鉴定incubationmedia酵母膏-麦芽膏琼脂ISPMedium2(YeastExtractMaltExtractAgar)250g/瓶用于链霉菌属的培养鉴定
大肠杆菌显色培养基 1000ml 用于快速、准确检测大肠杆菌,培
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蛋白质磷酸酶2A-B55抗体价格
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