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C-myc,c-MYC抗体

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  • ¥1000
  • affinty
  • AF0358
  • 2026年05月28日
  • WB,IHC,IF/ICC,ELISA
  • Human, Mouse, Rat
  • 详细信息
  • 文献和实验
  • 技术资料
  • 抗体名

    C-myc,c-MYC抗体

  • 适应物种

    Human, Mouse, Rat

  • 应用范围

    WB,IHC,IF/ICC,ELISA

  • 库存

    大量

  • 抗原来源

    其它

  • 供应商

    上海研卉生物科技有限公司

  • 是否单克隆

    多克隆

  • 宿主

  • 抗体英文名

    C-myc

  • 规格

    50μl

产品介绍癌基因蛋白C-myc是一种位于 细胞核内的转录因子,它由439个氨基酸组成,参与细胞的增殖、分化和凋亡等一系列过程。C-myc蛋白表面一共有7个磷酸化位点,其中2个是苏氨酸磷酸 化位点,5个是丝氨酸磷酸化位点。研究表面,在胃癌,乳腺癌,结肠癌和宫颈癌等许多肿瘤组织或细胞中,C-myc蛋白的表达量要明显高于正常的组织和细胞 中的表达量。

C-myc,c-MYC抗体

名 称:
c-MYC 抗体
货 号:
AF0358
来 源:
Rabbit
应 用:
WB,IHC,IF/ICC,ELISA
反 应:
Human, Mouse, Rat
预 测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
蛋白号:
P01106
分子量:
49kDa
浓 度:
1mg/ml

Applications:

WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Reference Citations:

1). Li C et al. Upregulation of E‑cadherin expression mediated by a novel dsRNA suppresses the growth and metastasis of bladder cancer cells by inhibiting β-catenin/TCF target genes. Int J Oncol 2018 Jun;52(6):1815-1826 (PubMed: 29620261) [IF=3.571]

2). Tang H et al. Neoisoliquiritigenin Inhibits Tumor Progression by Targeting GRP78-β- catenin Signaling in Breast Cancer. Curr Cancer Drug Targets 2018;18(4):390-399 (PubMed: 28914191)

3). Luo S et al. Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells. Oncol Lett 2018 Jan;15(1):483-488 (PubMed: 29375716)

4). Zhang Q et al. Enhancing E-cadherin expression via promoter-targeted miR-373 suppresses bladder cancer cells growth and metastasis. Oncotarget 2017 Sep 30;8(55):93969-93983 (PubMed: 29212202)

5). Tong Lu et al. Role of Wnt/β-catenin signaling pathway in the repair of intestinal mucosa associated with crypt stem cell in a rat model of abdominal compartment syndrome. Int J Clin Exp Pathol 2017;10(2):2351-2362

6). et al. Fungal Proteins from Hericium Erinaceus Show Auxiliary Antitumor Effects with 5-Fluoro-2,4(1H,3H)-Pyrimidinedione by Improving the Gut Microbiota in Mice.

7). et al. Fungal Proteins from Hericium Erinaceus Show Auxiliary Antitumor Effects with 5-Fluoro-2, 4 (1H, 3H)-Pyrimidinedione by Improving the Gut Microbiota in Mice.
Western blot analysis on 293 cell lysates using MYC Antibody,The lane on the left was treated with the antigen-specific peptide.
AF0358 at 1/100 staining Human breast cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
AF0358 staining 293 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.

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图标文献和实验
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  • 请教c-myc的序列

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  • 【求助】c-myc promoter 序列

    niukaiya 求助那位大侠能够给我C-MYC promoter序列,我已经找了很久,没有结果 zhujoker >8 dna:chromosome chromosome:GRCh37:8:128748330:128748869:1 CTGCTCGCGGCCGCCACCGCCGGGCCCCGGCCGTCCCTGGCTCCCCTCCTGCCTCGAGAA

  • Genome-Wide Analysis of c-MYC-Regulated mRNAs and miRNAs, and c-MYC DNA Binding by Next-Generation Sequencing

    The c-MYC oncogene is activated in ~50 % of all tumors, and its product, the c-MYC transcription factor, regulates numerous processes, which contribute to tumor initiation and progression. Therefore, the genome-wide characterization of c-MYC

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