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C-myc，c-MYC抗体

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  • ¥1000
  • affinty
  • AF0358
  • 2025年11月15日
  • WB,IHC,IF/ICC,ELISA
  • 兔
  • Human, Mouse, Rat
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上海研卉生物科技有限公司
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    • 文献和实验
    • 技术资料
    • 抗体名：

      C-myc，c-MYC抗体

    • 适应物种：

      Human, Mouse, Rat

    • 应用范围：

      WB,IHC,IF/ICC,ELISA

    • 库存：

      大量

    • 抗原来源：

      其它

    • 供应商：

      上海研卉生物科技有限公司

    • 是否单克隆：

      多克隆

    • 宿主：

      兔

    • 抗体英文名：

      C-myc

    • 规格：

      50μl

    【产品介绍】癌基因蛋白C-myc是一种位于 细胞核内的转录因子，它由439个氨基酸组成，参与细胞的增殖、分化和凋亡等一系列过程。C－myc蛋白表面一共有7个磷酸化位点，其中2个是苏氨酸磷酸 化位点，5个是丝氨酸磷酸化位点。研究表面，在胃癌，乳腺癌，结肠癌和宫颈癌等许多肿瘤组织或细胞中，C－myc蛋白的表达量要明显高于正常的组织和细胞 中的表达量。

    C-myc，c-MYC抗体

    名 称:
    c-MYC 抗体
    货 号:
    AF0358
    来 源:
    Rabbit
    应 用:
    WB,IHC,IF/ICC,ELISA
    反 应:
    Human, Mouse, Rat
    预 测:
    Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
    蛋白号:
    P01106
    分子量:
    49kDa
    浓 度:
    1mg/ml

    Applications:

    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    Reference Citations:

    1). Li C et al. Upregulation of E‑cadherin expression mediated by a novel dsRNA suppresses the growth and metastasis of bladder cancer cells by inhibiting β-catenin/TCF target genes. Int J Oncol 2018 Jun;52(6):1815-1826 (PubMed: 29620261) [IF=3.571]
    2). Tang H et al. Neoisoliquiritigenin Inhibits Tumor Progression by Targeting GRP78-β- catenin Signaling in Breast Cancer. Curr Cancer Drug Targets 2018;18(4):390-399 (PubMed: 28914191)
    3). Luo S et al. Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells. Oncol Lett 2018 Jan;15(1):483-488 (PubMed: 29375716)
    4). Zhang Q et al. Enhancing E-cadherin expression via promoter-targeted miR-373 suppresses bladder cancer cells growth and metastasis. Oncotarget 2017 Sep 30;8(55):93969-93983 (PubMed: 29212202)
    5). Tong Lu et al. Role of Wnt/β-catenin signaling pathway in the repair of intestinal mucosa associated with crypt stem cell in a rat model of abdominal compartment syndrome. Int J Clin Exp Pathol 2017;10(2):2351-2362
    6). et al. Fungal Proteins from Hericium Erinaceus Show Auxiliary Antitumor Effects with 5-Fluoro-2,4(1H,3H)-Pyrimidinedione by Improving the Gut Microbiota in Mice.
    7). et al. Fungal Proteins from Hericium Erinaceus Show Auxiliary Antitumor Effects with 5-Fluoro-2, 4 (1H, 3H)-Pyrimidinedione by Improving the Gut Microbiota in Mice.
    Western blot analysis on 293 cell lysates using MYC Antibody,The lane on the left was treated with the antigen-specific peptide.
    AF0358 c-MYC Antibody - N-terminal IHC Human breast cancer
    AF0358 at 1/100 staining Human breast cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
    AF0358 c-MYC Antibody - N-terminal IF/ICC 293
    AF0358 staining 293 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.

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