GEF; GLUT4 enhancer factor; HDBP 1; HDBP-1; HDBP1; Huntington disease gene regulatory region binding protein 1; Huntington disease gene regulatory region-binding protein 1; S2A4R_HUMAN; Si 1 2 19; Si 1 2; SLC2A4 regulator; SLC2A4RG; Zinc finger protein 2 5 Glut4 enhancer factor.
规格价格
100ul/2980元 购买 大包装/询价
说 明 书
100ul
研究领域
细胞生物 信号转导 转录调节因子 表观遗传学
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Cow, Sheep,
产品应用
IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
41kDa
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human SLC2A4RG/GLUT4 enhancer factor
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍
background: The protein encoded by this gene is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. The encoded protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene. [provided by RefSeq, Jul 2008].
Function: Transcription factor involved in SLC2A4 and HD gene transactivation. Binds to the consensus sequence 5'-GCCGGCG-3'.
Subunit: Interacts with MEF2A.
Subcellular Location: Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus.
Tissue Specificity: According to PubMed:14630949, expressed in heart, skeletal muscle, liver, kidney and pancreas; undetectable in lung, placenta or brain. According to PubMed:14625278, ubiquitously expressed, with lowest expression in brain and ileum.
Similarity: Contains 1 C2H2-type zinc finger.
Database links:
Entrez Gene: 56731 Human
Omim: 609493 Human
SwissProt: Q9NR83 Human
Unigene: 435126 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.