Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit,
适应物种:
Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit,
免疫原:
详见说明书
亚型:
IGg
形态:
粉末、液体、冻干粉
应用范围:
Flow-Cyt=1:10-500 ICC=1:50-200 IF=1:50-200
浓度:
1mg/ml
保存条件:
-20 °C
规格:
100ul
FITC标记的驱动蛋白KNS1抗体
英文名称
Anti-Kinesin/KIF5B/FITC
中文名称
FITC标记的驱动蛋白KNS1抗体
别 名
Conventional kinesin heavy chain; KIF5B; Kinesin 1 (110-120kD); Kinesin family member 5B; Kinesin heavy chain; Kinesin heavy chain ubiquitous; Kinesin-1 heavy chain; KINH; KINH_HUMAN; KNS 1; KNS; KNS1; Ubiquitous kinesin heavy chain; UKHC.
规格价格
100ul/2980元 购买 大包装/询价
说 明 书
100ul
研究领域
神经生物学 信号转导 细胞粘附分子 细胞骨架
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit,
产品应用
Flow-Cyt=1:10-500 ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
106kDa
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human Kinesin
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍
background: Structural proteins in Arabidopsis provide cellular stability, facilitate protein transportation within the cell and are essential for cell growth. Three types of molecular motors are involved in the organization, dynamics and transport processes associated with the cytoskeleton (1). They include myosin, which transports cargo along actin filaments, and kinesin and dynein, which transport cargo along microtubules (1,2). These proteins regulate many cellular functions, including cell division and expansion, cell-to-cell communication, membrane trafficking and morphogenesis (2). In addition, the dynamin-like proteins are GTP-binding proteins involved in vesicle trafficking (3). Extensin is a structural protein that may be involved in cell wall assembly, while expansin is a cell wall loosening protein that induces stress relaxation and extension of cell walls and may control organ size, morphology and abscission (4,5). Also, xyloglucan (XG), a major hemicellulose in plants, is modified by the fucosyltransferase, XG FTase, which adds a terminal fucosyl residue to XG (6).
Function: Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.
Subunit: Oligomer composed of two heavy chains and two light chains. Interacts with GRIP1 and PPP1R42 (By similarity). Interacts with SYBU. Interacts with JAKMIP1. Interacts with PLEKHM2. Interacts with ECM29.
Subcellular Location: Cytoplasm, cytoskeleton. Note=Uniformly distributed between soma and neurites in hippocampal neurons.
Similarity: Belongs to the kinesin-like protein family. Kinesin subfamily. Contains 1 kinesin-motor domain.
Database links:
Entrez Gene: 3799 Human
Entrez Gene: 16573 Mouse
Entrez Gene: 117550 Rat
Omim: 602809 Human
SwissProt: P33176 Human
SwissProt: Q61768 Mouse
SwissProt: Q2PQA9 Rat
Unigene: 327736 Human
Unigene: 644646 Human
Unigene: 223744 Mouse
Unigene: 4046 Rat
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.