Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Sheep,
适应物种:
Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Sheep,
免疫原:
详见说明书
亚型:
IGg
形态:
粉末、液体、冻干粉
应用范围:
ICC=1:50-200 IF=1:50-200
浓度:
1mg/ml
保存条件:
-20 °C
规格:
100ul
FITC标记的环指蛋白60抗体
英文名称
Anti-MID2/FITC
中文名称
FITC标记的环指蛋白60抗体
别 名
FXY2; MID2; Midin-2; Midline 2; Midline defect 2; Midline-2; Probable E3 ubiquitin-protein ligase MID2; RING finger protein 60; Ring finger protein protein 60; RNF60; TRIM1; TRIM1_HUMAN; Tripartite motif protein 1; Tripartite motif-containing protein 1; Tripartite motif-containing protein 1; Midline defect 2; FLJ37715; FLJ41813.
规格价格
100ul/2980元 购买 大包装/询价
说 明 书
100ul
研究领域
神经生物学 信号转导 细胞周期蛋白 细胞粘附分子 细胞骨架 泛素
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Sheep,
产品应用
ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
83kDa
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human Midline-2
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍
background: Midline-2 is a 715 amino acid protein encoded by the human gene MID2. Midline-2 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, one B30.2/SPRY domain, one COS domain, one fibronectin type-III domain and one RING-type zinc finger. Midline-2 is a cytoplasmic protein found as a homodimer or heterodimer with Midline-1. It also interacts with IGBP1 (Lymphocyte signaling protein A4). Dimerization is mediated by the tripartite motif (RBCC; RING- and B box-type zinc fingers and coiled coil domains) and microtubule association is dependent on the C-terminal B30.2 domain. Midline-2 is expressed at low levels in fetal kidney and lung, and in adult prostate, ovary and small intestine.
Subunit: Homodimer or heterodimer with MID1. Interacts with IGBP1.
Tissue Specificity: Low level in fetal kidney and lung, and in adult prostate, ovary and small intestine.
Post-translational modifications: Phosphorylated on serine and threonine residues.
Similarity: Belongs to the TRIM/RBCC family. Contains 2 B box-type zinc fingers. Contains 1 B30.2/SPRY domain. Contains 1 COS domain. Contains 1 fibronectin type-III domain. Contains 1 RING-type zinc finger.
Database links:
Entrez Gene: 422131 Chicken
Entrez Gene: 11043 Human
Entrez Gene: 23947 Mouse
Entrez Gene: 100157515 Pig
Entrez Gene: 363502 Rat
Omim: 300204 Human
SwissProt: Q9UJV3 Human
SwissProt: Q9QUS6 Mouse
Unigene: 12256 Human
Unigene: 131097 Mouse
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.