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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
Beta-Amyloid (1-42), Ultra Pure, HFIP
- 保质期:
2年
- 库存:
0.5mg/支、1mg/支
- 供应商:
豪地华拓
- 保存条件:
- 20℃
- 规格:
1.0mg

DATA SHEET
Catalog #: A-1163-2
Source: Recombinant. A DNA sequence encoding the human beta-amyloid
(1-42) sequence was expressed in E. coli.
Sequence: D A E F R H D S G Y E V H H Q K L V F F A E D V G S N K G A I I G L M V G G V V I A
Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-
Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala
Molecular Mass: 4514.1
Peptide Purity: >97%
Counter Ion: HFIP treated
Supplied As: No salt, as HFIP desalts the sample.
Resuspension: Resuspend in 1 % NH4OH, at a concentration of 1 mg/ml. Sonicate for 30
seconds to 1 minute after it has gone into solution.
To bring it into your buffer: After resuspension, add 5x or 10x buffer stock
and water, to bring to 1x buffer.
Storage: –20℃
Description: Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be the cause of Alzheimer’s Disease (AD)1-3. AD is the most common neurodegenerative disease and afflicts about 10% of the population over 604. The abeta,HFIP is described in Stine, et. al.3.
References:
1) Yankner, BA, et. al., (1990) Science, 250: 279-282
2) Selkoe, D.J., (2001) Physiol. Rev, 81: 741-766
3) Stine, W.B. et. al., (2003) J. Biol. Chem, 278: 11612-11622
4) Frank, R.A., et. al., (2003) Neurobiology of Aging, 24: 521-536
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