Human, Mouse, Rat, Dog, Pig, Cow, Sheep, Zebrafish
适应物种:
Human, Mouse, Rat, Dog, Pig, Cow, Sheep, Zebrafish
免疫原:
详见说明书
亚型:
IGg
形态:
粉末、液体、冻干粉
应用范围:
ICC=1:50-200 IF=1:50-200
浓度:
1mg/ml
保存条件:
-20 °C
规格:
100ul
FITC标记的高度保守基因相关蛋白Membralin抗体
英文名称
Anti-Membralin/FITC
中文名称
FITC标记的高度保守基因相关蛋白Membralin抗体
别 名
ASBABP1; C19orf6; MGC4022; R32184_3; aspecific BCL2 ARE-binding protein 1; C19orf6; chromosome 19 open reading frame 6; MBRL; MBRL_HUMAN.
规格价格
100ul/2980元 购买 大包装/询价
说 明 书
100ul
研究领域
肿瘤 细胞生物 神经生物学 肿瘤细胞生物标志物
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Mouse, Rat, Dog, Pig, Cow, Sheep, Zebrafish
产品应用
ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
68kDa
细胞定位
细胞膜
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human Membralin
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍
background: The gene encoding human Membralin, C19orf6, localizes to chromosome 19p13.3. It contains 11 exons, which encode at least two splice variants in human cancer. Membralin is a multi-pass membrane protein and exists either as a long or short form. The long form of Membralin comprises all 11 exons, while the short form contains all exons except exon 10. Expression of different Membralin isoforms depends on tissue type. The long form is expressed in ovarian and colorectal carcinomas, whereas the short form is expressed in breast or pancreatic carcinomas. Because Membralin expression in ovarian carcinomas is highest in serous carcinomas as compared to surface epithelium carcinomas, expression of Membralin may be useful as a novel tumor-associated marker in ovarian serous carcinomas.
Function: Membralin has been reported to be a protein expressed in the central nervous system and has also been identified as a novel tumor associated marker in ovarian serous carcinomas.
Subcellular Location: Membrane; Multi-pass membrane protein. Cytoplasm.Note=Cytoplasmic according to PubMed:16084606.
Database links:
Entrez Gene: 91304 Human
Omim: 611011 Human
SwissProt: Q4ZIN3 Human
Unigene: 515003 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.