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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
- 保质期:
参照说明书可保存1-2年
- 英文名:
TAT Peptide
- 库存:
一定量库存
- 供应商:
华拓生物
- 规格:
1 mg
| 产品名称: | TAT Peptide |
| 产品链接: | http://www.abbiotec.com/peptides/tat-peptide |
| 货号: | 350402 |
| 规格: | 1 mg |
| 产品描述: | TAT protein is the nuclear transcriptional activator of viral gene expression in HIV proliferation. The TAT peptide corresponds to the polycationic aa49-57 region of TAT protein. TAT peptide is a cell-penetrating peptide (CPP) used to cargo larger molecules through the lipophilic barrier of the cellular membranes to deliver them inside the cells with intact biological activity. These peptides are also known as protein transduction domains (PTD). |
| 序列: | Human: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2 or H-YGRKKRRQRRR-NH2 |
| 分子式: | C64H119N33O13 |
| 分子量: | 1558.88 g/mol |
| 纯度: | Purity > 95% by HPLC |
| 别名: | Tat protein; transactivator of transciption protein; transactivating regulatory protein |
| 形态: | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| 溶解方法: | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法: | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
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文献和实验liufengxi HIV-1 Tat (47-57) N-term Cys 序列 H-CYGRKKRRQRRR-NH2 ;原始HIV-1 Tat (47-57)序列为YGRKKRRQRRR 。N端的半胱氨酸修饰是为了利用其含有的巯基和其他分子反应,但是C端得-NH2的修饰是什么目的呢?有这个修饰的必要吗?是为了增强多肽的活性,还是发挥一个阻断活性COOH的作用? 附件是关于HIV-1 Tat (47-57) N-term Cys的产品介绍。请高手
Disrupting Protein Complexes Using Tat-Tagged Peptide Mimics
to specifically modulate certain signaling pathways. Tat-tagged peptide mimics are a recently developed experimental tool that is used to disrupt specific interactions between protein complexes. TAT, an 11-amino acid protein transduction domain from HIV Tat
TAT-Peptide Modified Liposomes: Preparation, Characterization, and Cellular Interaction
compartment. Therefore, bypassing the endocytic route by conferring a direct plasma membrane translocation property to the liposomes would be very beneficial. Cell penetrating peptides, e.g. TAT-peptide, are exploited in the drug delivery field
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