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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
- 保质期:
参照说明书可保存1-2年
- 英文名:
Pancreatic Polypeptide
- 库存:
一定量库存
- 供应商:
华拓生物
- 规格:
1 mg
| 产品名称: | Pancreatic Polypeptide |
| 产品链接: | http://www.abbiotec.com/peptides/pancreatic-polypeptide |
| 货号: | 350327 |
| 规格: | 1 mg |
| 产品描述: | The pancreatic prohormone (Pancreatic Polypeptide or PPY) is synthesized in the pancreatic islets of Langherans. PPY regulates pancreatic and gastrointestinal functions. PPY is cleaved into 2 chains, a 36-aa pancreatic hormone (PH, Cat. No. 350327, human sequence) and a 20-aa pancreatic icosapeptide (PI). Obinepitide, a PPY derivative with Gln63, is tested in clinical trials for the treatment of obesity. |
| 序列: | Human: H-Ala-Pro-Leu-Glu-Pro-Val-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Asp-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2 or H-APLEPVYPGDNATPEQMAQYAADLRRYINMLTRPRY-NH2 |
| 分子式: | C185H287N53O54S2 |
| 分子量: | 4181.8 g/mol |
| 纯度: | Purity > 95% by HPLC |
| 别名: | Pancreatic prohormone; Pancreatic polypeptide; PP; Obinepitide; PPY; PNP; Pancreatic hormone |
| 形态: | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| 溶解方法: | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法: | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
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文献和实验多数氨基酸以肽键结合而成的化合物。狭义上一般是指蛋白质除外的物质,但实际上蛋白质和多肽是不可分开的。
Culture of Human Pancreatic Islet Cells
, which are mainly located in the center of the islet, are the insulin-producing �;β-cells In the periphery, α-cells and δ-cells synthesizing glucagon and somatostatin, respectively, are found. Finally, a small number of cells containing pancreatic polypeptide (PP
多肽链延伸因子 polypeptide chain elonga-tion factor
蛋白质生物合成中参与多肽链延伸过程的蛋白质因子。从大肠杆菌等原核细胞可纯化获得三种延伸因子(elongation factor),即EFTu,EFTs和EFG,分子量大约分别为4.7万,3.6万和8.3万。EFTu与GTP结合成EFTu-GTP,然后再与氨酰tRNA结合,形成三复合体(ternary complex)氨酰-tRNA-EFTu-GTP。这种三复合体与核糖体的氨酰tRNA部位(A部位,aminoacyl site)结合,继而GTP被分解,EFTu以EFTu-
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