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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
- 保质期:
参照说明书可保存1-2年
- 英文名:
Big Endothelin 1 [1-38] Peptide
- 库存:
一定量库存
- 供应商:
华拓生物
- 规格:
1 mg
| 产品名称: | Big Endothelin 1 [1-38] Peptide |
| 产品链接: | http://www.abbiotec.com/peptides/big-endothelin-1-%25255B1-38%25255D |
| 货号: | 350085 |
| 规格: | 1 mg |
| 产品描述: | Endothelins are endothelium-derived vasoconstrictor peptides. Endothelin-1 is expressed as a 212-aa precursor (preproendothelin-1) that is sequentially cleaved into 2 chains: Endothelin-1 (21 aa) and Big Endothelin-1 (38 aa). Big endothelin-1 is cleaved to yield endothelin-1 via the activity of an endothelin-converting enzyme (ECE). Big Endothelin-1 can be hydrolyzed by chymase to generate endothelin 1 (1-21) in vitro. |
| 序列: | Human: H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Val-Val-Pro-Tyr-Gly-Leu-Gly-Ser-Pro-Arg-Ser-OH (Cys1-Cys15, Cys3-Cys11) or H-CSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGLGSPRS-OH (Cys1-Cys15, Cys3-Cys11) |
| 分子式: | C189H282N48O56S5 |
| 分子量: | 4282.96 g/mol |
| 纯度: | Purity > 95% by HPLC |
| 别名: | Big endothelin-1; endothelin-1; preproendothelin-1; PPET1; ET-1; EDN1 |
| 形态: | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| 溶解方法: | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法: | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
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文献和实验Methods for analysis of matrix metalloproteinase regulation of neutrophil-endothelial cell adhesion
. We have previously reported that MMP-2 can modulate vascular reactivity by cleavage of the Gly32-Leu33 bound in big endothelin-1 (ET-1) yielding a novel vasoactive peptide ET-1[1–32]. These studies were conducted to investigate whether gelatinolytic MMPs could affect
【分享】Human press METHODS IN MOLECULAR BIOLOGY
. Edited by Endothelin Maguire, Janet J. 2002 207.Recombinant Antibodies for Cancer Therapy Methods and Protocols. Edited by Welschof, Martin 2002 208.Peptide Nucleic Acids Methods and Protocols. Edited by Nielsen, Peter E. 2002 209.Transgenic Mouse
Scintillation Proximity Assay (SPA) Technology to Study Biomolecular Interactions
released is dissipated before reaching the bead, and these disintegrations are not detected. In this unit, the application of SPA technology to measuring protein?protein interactions, Src Homology 2 (SH2) and 3 (SH3) domain binding to specific peptide
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