- ￥600 - 1600
- Abbiotec
- 美国
- 350011
- 2025年06月27日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
- 保质期：
参照说明书可保存1-2年
- 英文名：
Tyr-Specific Protein Kinase Inhibitor Peptide
- 库存：
一定量库存
- 供应商：
华拓生物
- 规格：
1 mg
| 产品名称： | Tyr-Specific Protein Kinase Inhibitor Peptide |
| 产品链接： | http://www.abbiotec.com/peptides/tyr-specific-protein-kinase-inhibitor%2525C2%2525A0peptide |
| 货号： | 350011 |
| 规格： | 1 mg |
| 产品描述： | This peptide is an inhibitor for tyrosine protein kinases such as EGFR and Src subfamily members (IC50 = 7.5 mM for pp60 v-src). The sequence corresponds to residues 140-160 of the proto-oncogene tyrosine protein kinase Src (c-Src). |
| 序列： | Val-Ala-Pro-Ser-Asp-Ser-Ile-Gln-Ala-Glu-Glu-Trp-Tyr-Phe-Gly-Lys-Ile-Thr-Arg-Arg-Glu or VAPSDSIQAEEWYFGKITRRE |
| 分子式： | C111H168N30O33 |
| 分子量： | 2482.8 g/mol |
| 纯度： | Purity > 95% by HPLC |
| 别名： | Proto-oncogene tyrosine-protein kinase Src; p60-Src; c-Src; pp60c-src; SRC; SRC1 |
| 形态： | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| 溶解方法： | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法： | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
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文献和实验Random Mutagenesis of Peptide Aptamers as an Optimization Strategy for Inhibitor Screening
and the highly combinatorial libraries available, this approach yields rapidly highly specific candidate inhibitors. Once a hit peptide has been identified, its interaction strength and affinity towards its target protein can be optimized even more, in order
DNA-Dependent Protein Kinase in Apoptosis
of the peptide bond following specific aspartic acid residues ( 6 ). This class of proteases has been termed caspases for cysteinyl, aspartate-specific proteases. A current view of the caspase cascade is presented in Fig. 1 . Genotoxic stress results
The inflammatory response requires complex and coordinated cooperation of different signaling pathways and cell types. Therefore, more than 40 different protein or lipid kinases can be regarded as potential small-molecule inhibitor targets
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