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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
- 保质期:
参照说明书可保存1-2年
- 英文名:
CaMKII [290-309] Inhibitory Peptide
- 库存:
一定量库存
- 供应商:
华拓生物
- 规格:
1 mg
| 产品名称: | CaMKII [290-309] Inhibitory Peptide |
| 产品链接: | http://www.abbiotec.com/peptides/camkii-%25255B290-309%25255D-inhibitory-peptide%2525C2%2525A0 |
| 货号: | 350006 |
| 规格: | 1 mg |
| 产品描述: | This peptide is a potent calmodulin antagonist and an inhibitor for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family. The sequence derives from the residues 290-309 within the calmodulin-binding domain of human CaMKII alpha. CaMKII is a prominent kinase in the central nervous system that functions in long-term potentiation and neurotransmitter release. This peptide inhibits CaMKII activation by blocking calmodulin binding to CaMKII. |
| 序列: | Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala or LKKFNARRKLKGAILTTMLA |
| 分子式: | C103H185N31O24S1 |
| 分子量: | 2273.9 g/mol |
| 纯度: | Purity > 95% by HPLC |
| 别名: | Calcium/calmodulin-dependent protein kinase type II alpha chain; CaM-kinase II alpha chain; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2A; CAMKA; KIAA0968 |
| 形态: | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| 溶解方法: | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法: | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
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文献和实验spectrophotometer. Measure by non-destructive fluorometry. Histones can be detected by an excitation wavelength of 280 nm and a fluorescence measurement at 308 nm. Non-histones can be detected in the same sample by excitation at 290 nm
抑制荷尔蒙 inhibitory hormone 指大猎椿象的咽侧体( corpus allatum)激素(保幼激素)。最初是由威格尔斯沃思( V. B. wi-gglesworth, 1934)所使用的词,这是根据这种激素可抑制成虫变态而命名的。
Neuronal Growth-Promoting and Inhibitory Cues in Neuroprotection and Neuroregeneration
with learning and memory. Synthetic NCAM peptide mimetics corresponding to the binding site of NCAM for the fibroblast growth factor receptor promote synaptogenesis, enhance presynaptic function, and facilitate memory consolidation. Dimeric versions
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