- ￥600 - 1600
- Abbiotec
- 美国
- 350003
- 2025年07月11日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
- 保质期：
参照说明书可保存1-2年
- 英文名：
Autocamtide-2 Peptide
- 库存：
一定量库存
- 供应商：
华拓生物
- 规格：
1 mg
| 产品名称： | Autocamtide-2 Peptide |
| 产品链接： | http://www.abbiotec.com/peptides/autocamtide-2%2525C2%2525A0-peptide |
| 货号： | 350003 |
| 规格： | 1 mg |
| 产品描述： | Autocamtide-2 is a highly selective peptide substrate for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family. The sequence derives from the Thr-286 autophosphorylation site of the alpha subunit of CaMKII. Autocamtide-2 contains the R-X-X-S/T consensus site surrounded by basic residues for improved binding to phosphocellulose. CaMKII is a prominent kinase in the central nervous system that functions in long-term potentiation and neurotransmitter release. Autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CaMKII phosphorylates Autocamtide-2 with a Km of 2 uM whereas protein kinase C (PKC) has a Km > 50 uM and protein kinase A (PKA) has no activity. |
| 序列： | Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu or KKALRRQETVDAL |
| 分子式： | C65H118N22O20 |
| 分子量： | 1527.8 g/mol |
| 纯度： | Purity > 95% by HPLC |
| 别名： | Calcium/calmodulin-dependent protein kinase type II alpha chain; CaM-kinase II alpha chain; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2A; CAMKA; KIAA0968 |
| 形态： | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| 溶解方法： | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法： | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验分子肽也天然存在。一般为无色微粉状结晶。熔点（分解点）为 200— 250℃左右，大多可溶于水、酸和碱中，难溶于有机溶剂。随着分子量的增大，变得难溶于水，水溶液变成象天然蛋白质那样起泡沫，可被盐析。三肽以上可显示双缩脲反应。水解则产生氨基酸。环状肽常见于抗菌物质（短杆菌肽等）。
,with the development of ESI-MS and MALDI-MS.Peptide mass fingerprinting uses the peptide masses obtained by digestion to search the protein and DNA databases,to find proteins that show a similar theoretical digest pattern (see eg .,Shevchenko et al.1996a and b
Two dimensional peptide mapping
This specfic protocol is the latest incarnation of peptide mapping procedures that have been developed here in the TVL/MBVL of the Salk Institute over the last 20 years. Wade Gibson developed the first peptide mapping protocol
技术资料暂无技术资料 索取技术资料
