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NRXN3 Rabbit pAb(bs-20614R)-50

ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-20614R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-20614R
    英文名称NRXN3 Rabbit pAb
    中文名称轴突蛋白3抗体
    英文别名Neurexin III-alpha; NRXN3; NRXN 3; NRXN-3; C14orf60; Neurexin 3; Neurexin3; Neurexin-3; Neurexin III; Neurexin III-alpha; Neurexin-3-alpha [Precursor]; NRX3A_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human NRXN3
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量178 kDa
    浓度1mg/ml
    储存液Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
    研究领域

    Neuroscience > Cell Adhesion Proteins > Membrane Proteins

    Neuroscience > Cell Type Marker > Neuron marker > Synapse marker

    亚基The cytoplasmic C-terminal region binds to CASK. Binds to neuroligins NLGN1, NLGN2 and NLGN3.
    亚细胞定位Membrane; Single-pass type I membrane protein (Potential).
    组织特异性Expressed in the blood vessel walls (at protein level).
    翻译后修饰Proccessed by alpha-secretase leading to the formation of an extracellular soluble protein as well as a C-terminal membrane-embedded fragment (CTF). Proteolysis of these CTFs by gamma-secretase releases intracellular domains (ICDs) and extracellular peptides.
    相似性Belongs to the neurexin family.
    Contains 1 laminin G-like domain.
    功能Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May play a role in angiogenesis.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder. [provided by RefSeq, Dec 2012]

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    Hela(Human) Cell Lysate at 40 ug
    Primary: Anti-alpha smooth muscle Actin (bs-10196R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 178 kD
    Observed band size: 117 kD

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    ¥1180 - 2800