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- 2025年10月10日
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| 产品编号 | bs-0411Rs |
| 英文名称 | Rabbit Anti-human IgG heavy chain constant region whole serum |
| 中文名称 | 兔抗人IgG（γ-链）恒定区抗血清 |
| 英文别名 | Ig gamma 1 chain C region; IGHG1; Immunoglobin heavy constant gamma 1; Immunoglobulin G. |
| 中文别名 | 兔抗人IgG（γ-链）恒定区抗血清 |
| 产品应用 | WB=1:10000-50000, IHC-P=1:100-500, IHC-F=1:10000-50000, IF, ELISA=1:10000-100000 Not yet tested in other applications. |
| 交叉反应 | Human |
| 抗体来源 | Rabbit |
| 免疫原 | human IgG heavy chain |
| 性状 | Liquid |
| 克隆类型 | Polyclonal |
| 保存条件 | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Immunoglobulin G (IgG), is one of the most abundant proteins in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:10000-50000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:10000-50000} |
| {ELISA} | {1:10000-100000} |
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文献和实验Production of Chimeric Heavy-Chain Antibodies
of fragment crystallizable (Fc), which is known to be crucial for a long serum half-life through binding to FcRn and antibody-mediated cell killing through binding to Fcγ receptors and complement. Single-domain antibodies (sdAbs) derived from camelid heavy
Use of Lectin for Detection of Agalactosyl IgG
The immunoglobulin G (IgG) molecule contains two biantennary complextype oligosaccharide chains, each linked to the heavy chain at asparagine 297 within the CH2 domain ( 1 ) ( see Note 1 ). X-ray
Immunoglobulin Class Switching: In Vitro Induction and Analysis
of the gene segments coding for the constant region of the Ig heavy chain, although the Ig heavy chain variable region is retained. This process changes the effector functions of the corresponding antibody (Ab). Much of our current understanding
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