The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
克隆性:
多克隆
供应商:
安诺伦(北京)生物科技有限公司
应用范围:
FC, FA
规格:
500 μg
研究领域:Angiogenesis
来源:Armenian Hamster IgG
存储溶液:Phosphate-buffered aqueous solution, ph7.2.
参考文献:Ridger, V. C., Wagner, B. E., Wallace, W. A., & Hellewell, P. G. (2001). Differential effects of CD18, CD29, and CD49 integrin subunit inhibition on neutrophil migration in pulmonary inflammation. The Journal of Immunology,166(5), 3484-3490.Noto, K., Kato, K., Okumura, K., & Yagita, H. (1995). Identification and functional characterization of mouse CD29 with a mAb. International immunology, 7(5), 835-842.Sangaletti, S., Di Carlo, E., Gariboldi, S., Miotti, S., Cappetti, B., Parenza, M., ... & Colombo, M. P. (2008). Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis. Cancer research, 68(21), 9050-9059.
简单描述:The HMb1-1 monoclonal antibody specifically reacts with mouse/rat CD29, a 130 kDA molecule also known as integrin beta 1, GPIIa, and the VLA-beta chain. It is expressed broadly on endothelial cells, epithelial, leukocytes, and smooth muscle. CD29 forms the VLA 1-6 complexes through the non-covalent interaction with the alpha integrins of CD49 a-f. The HMb1-1 antibody is capable of inhibiting T cell proliferation and blocking cell adhesion.