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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海联迈生物工程有限公司
- 库存:
大量
- 目录编号:
LM-8420R
- 克隆性:
多克隆
- 抗原来源:
Rabbit
- 保质期:
1年
- 抗体英文名:
VAT1L
- 抗体名:
囊泡胺转运蛋白1家族蛋白抗体
- 宿主:
Rabbit
- 适应物种:
Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Sheep,
- 免疫原:
KLH conjugated synthetic peptide derived from human KIAA1576/VAT1L:171-270/419
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复)
- 浓度:
1mg/ml
- 保存条件:
Store at -20 °C
- 规格:
100ul 200ul
| 英文名称 | VAT1L |
| 中文名称 | 囊泡胺转运蛋白1家族蛋白抗体 |
| 别 名 | Probable oxidoreductase KIAA1576; Synaptic vesicle membrane protein VAT 1 homolog like; Synaptic vesicle membrane protein VAT-1 homolog-like; VAT 1L; VAT1L; VAT1L_HUMAN; Vesicle amine transport protein 1 homolog (T. californica) like. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Sheep, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 46kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KIAA1576/VAT1L:171-270/419 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The KIAA1576 gene product has been provisionally designated KIAA1576 pending further characterization. Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. SWISS: Q9HCJ6 Gene ID: 57687 Database links: Entrez Gene: 57687 Human SwissProt: Q9HCJ6 Human Unigene: 461405 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 | ![]() Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (VAT1L) Polyclonal Antibody, Unconjugated (bs-8420R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. |
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文献和实验肝细胞的标志——醛缩酶 B mRNA 的水平,达到新鲜分离的人肝细胞 20% 的水平。相比 HepaG2 细胞,其白蛋白和触珠蛋白 mRNA 的表达水平比 HepaRG 细胞低,检测不到醛缩酶 B 的转录。二、药物代谢相关酶系细胞色素 P450(CYP)是最大的药物代谢酶蛋白超家族之一,其中参与人体肝药物代谢的主要有 CYP1、CYP2、CYP3 及 CYP4 家族。P450 酶易受多种内外源性物质的诱导或抑制,导致酶数量和活性改变,从而改变药代动力学,使药物活性物质累积导致毒性增强或降低其血
据估计细胞膜上与物质转运有关的蛋白占核基因编码蛋白的15~30%,细胞用在物质转运方面的能量达细胞总消耗能量的2/3。细胞膜上存在两类主要的转运蛋白,即:载体蛋白(carrier protein)和通道蛋白(channel protein)。载体蛋白又称做载体(carrier)、通透酶(permease)和转运器(transporter),有的需要能量驱动,如:各类APT驱动的离子泵;有的则不需要能量,如:缬氨酶素。通道蛋白能形成亲水的通道,允许特定的溶质通过,所有通道蛋白均以自由扩散的方式
P07900) 和鼠免疫球蛋白重链结合蛋白(BIP , Swiss-Prot P06767) 蛋白抗体制作成抗体阵列,可以检测某种蛋白达到10fm/μl。美国科学家Haab 等运用绿色荧光(green fluorescence) 标记抗体微阵列,用红色荧光(red fluorescence) 标记蛋白混和物,并运用计算机识别(R/ G)的信号强弱,来进行检测,检测水平可达到1ng/ ml [11] 。③蛋白质芯片具有高度的准确性。 3 蛋白质芯片的运用 蛋白质组芯片可用于蛋白
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