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10µg
靶点/蛋白质:ALDTNYCFR NLEENCCVR PLYIDFRQD LGWKWVHEP KGYYANFCS GPCPYLRSA DTTHSTVLG LYNTLNPEA SASPCCVPQ DLEPLTILY YVGRTPKVE QLSNMVVKS CKCS
特异性:Cow, Dog, Mouse, Pig, Rat
官网链接:http://www.bio-gems.com/recombinant-proteins/animal-free-cytokines/animal-free-recombinant-human-tgf-3-e-coli-derived.html
商品关键词:Animal-Free Recombinant Human TGF-β3 (E.coli derived),AF-100-36E-10µg ,Biogems
简单描述:The three mammalian isoforms of TGF-β, TGF-β1, β2, β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and /or induction of conformational changes by proteins such as thrombospondin-1. The physiological role of TGF-β3 is still unknown but its expression pattern suggests a role in the regulation of certain development processes. Recombinant human TGF-β3 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond. Manufactured using all non-animal reagents.
Purity: Above 154% as determined by SDS-PAGE Analysis.
Biological Activity: The ED50 was determined by TGF-β3’s ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥2 x 10<
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文献和实验Human Embryonic Stem Cells Derived in Xeno-Free Conditions
In this chapter, we describe the derivation and characterization of nine hIn this chapter, we describe the derivation and characterization of nine human embryonic stem cells (hESC) (VAL-3 to -11B) from different developmental embryo stages
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Characterization and Applications of Plant-Derived Recombinant Antibodies
Expression of foreign proteins in plants has become a standard technique in plant molecular biology. Various plant species have been used to produce mammalian proteins, such as human interferon (1 ) and serum albumin (2 ), as well as murine
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