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- Biogems
- AF-120-05ET-10µg
- 美国
- 2025年07月07日
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靶点/蛋白质：KKNKNCRRH SLYVDFSDV GWNDWIVAP PGYQAFYCH GDCPFPLAD HLNSTNHAI VQTLVNSVN SSIPKACCV PTELSAISM LYLDEYDKV VLKNYQEMV VEGCGCR
特异性：Mouse
官网链接：http://www.bio-gems.com/recombinant-proteins/animal-free-cytokines/animal-free-recombinant-human-bmp-4.html
商品关键词：Animal-Free Recombinant Human BMP-4,AF-120-05ET-10µg ,Biogems
简单描述：Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. The E.coli derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor. Manufactured using all non-animal reagents.
Purity: Above 97% as determined by SDS-PAGE Analysis.
Biological Activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml.
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