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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
2089647-47-0
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥1135.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥621.0 |
| 规格: | 5 mg | 产品价格: | ¥1500.0 |
| 规格: | 10 mg | 产品价格: | ¥2400.0 |
| 规格: | 25 mg | 产品价格: | ¥4800.0 |
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SGN-2FF
CAS No. : 2089647-47-0
MCE 国际站:SGN-2FF
产品活性:SGN-2FF 是一种有效的,具有口服活性的岩藻糖基化抑制剂,抑制岩藻糖基转移酶 (fucosyltransferase) 的活性,具有抗肿瘤活性。
研究领域:Others
作用靶点:Others
In Vitro: SGN-2FF (2-Fluorofucose) is an inhibitor of fucosylation, inhibits cellular fucosylation by depleting the fucosylation substrate GDP-fucose, and by direct inhibition of fucosyltransferases, and leads to the production of afucosylated glycoproteins including antibodies. SGN-2FF activates human T cells in an antigen-dependent manner.
In Vivo: SGN-2FF exhibits antitumor activity in multiple mouse tumor models, showing substantial tumor growth delay. SGN-2FF elevates the protective effect of a lymphoma vaccine in a syngeneic mouse model.
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文献和实验一.测定1.把蓄电池接到2个蓄电池插孔中的任一个,干燥管中换入新的干燥剂,打开电源开关,显示器将闪烁。接着瞬息指示“Pad Cleared”(页已清除),然后显示软件版本“LI—6200.02.00”2.检查蓄电池电压与内存容量(按U键)。3.检查页参数(按SETU或FCT41)。4.检查时钟和校正表(按FCT43:时钟,FCT44:量子传感器;FCT45:C02分析器;FCT46:流量计;FCT47:湿度传感器。5.流量计凋零(按FCT48)。6.设置分析器参数(按FCT49)。7.设置LI
Sequenase Reaction Buffer (5X concentrate):200 mM Tris-HCl (pH 7.5),100 mM MgCl2,250 mM NaCl o pUC/M13 forward (-47) primer: 5"-d(CGCCAGGGTTTTCCCAGTCACGAC)-3" o 四种Termination Mix: 均含50 mM NaCl,80 M dATP,80 M dGTP,80 M dCTP,80 M dTTP,并各含8 M
Ref No. L8102 1 mg: 620 FF + 26% VAT plus Shipping & Handling 5 mg: 2480 FF + 26% VAT plus Shipping & Handling * Latoxan is used to delivering abroad, and they will ship by express courier if desired. Alternatively, cardiotoxin from Sigma
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