All LSBio Custom kits have been predesigned and all necessary components, including antibodies and standards have been identified. Upon receiving a custom kit order, the kit will be assembled and quality control tested before being shipped out. Kit assembly and testing typically takes 4 to 6 weeks. In most cases the final kit is based on the Sandwich assay principle, with a few being Competitive EIA based. Specifications such as Range, Sensitivity, and Precision are defined upon completion. In the event that the custom kit cannot be successfully developed with 6 weeks of the order date, the customer will be notified and the order canceled at no cost.
ATP13A2
Mouse
LS-F19897 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the detection of Mouse ATP13A2. It is based upon a Custom assay principle.
ATP13A2 belongs to the P-type superfamily of ATPases that transport inorganic cations and other substrates across cell membranes. ATP13A2 has predominantly neuronal expression and transiently transfected cells studies have shown that it is located in lysosomes. Recently a loss-of-function mutation in ATP13A2 has been linked to an autosomal recessive form of early-onset parkinsonism with pyramidal degeneration and dementia.
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