HSD3B1滋养层细胞抗原3β-HSD抗体

HSD3B1滋养层细胞抗原3β-HSD抗体

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  • ¥780 - 2200
  • LMAI Bio
  • LM-3906R
  • 进口/国产
  • 2025年11月06日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Human, Mouse, Rat, Dog, Cow, Horse,
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    • 详细信息
    • 询价记录
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-3906R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      HSD3B1

    • 抗体名

      滋养层细胞抗原3β-HSD抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Cow, Horse,

    • 免疫原

      KLH conjugated synthetic peptide derived from human HSD3B1:301-373/373

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      50ul  100ul  200ul

    HSD3B1滋养层细胞抗原3β-HSD抗体
    英文名称 HSD3B1
    中文名称 滋养层细胞抗原3β-HSD抗体
    别    名 3 beta and steroid delta isomerase 1; 3 beta and steroid hydroxy delta 5 steroid dehydrogenase; 3 beta HSD I; 3BH; 3BHSD; HGNC:5217; HSD3B; HSD3B1; HSDB3; HSDB3A; Hydroxy delta 5 steroid dehydrogenase 3 beta and steroid delta isomerase 1; Hydroxy delta 5 steroid dehydrogenase; trophoblast antigen; 3BHS1_HUMAN; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; Short=3-beta-HSD I; Trophoblast antigen FDO161G; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase; 3-beta-hydroxy-5-ene steroid dehydrogenase; Progesterone reductase; Steroid Delta-isomerase; Delta-5-3-ketosteroid isomerase.   
    规格价格 50ul/780元 购买    100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 50ul  100ul  200ul
    研究领域 肿瘤  细胞生物  免疫学  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 41kDa
    细胞定位 细胞浆 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human HSD3B1:301-373/373 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]

    Subcellular Location:
    Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.

    Tissue Specificity:
    Placenta and skin. Predominantly expressed in mammary gland tissue.

    Similarity:
    Belongs to the 3-beta-HSD family.

    SWISS:
    P14060

    Gene ID:
    3283

    Database links:

    Entrez Gene: 3283 Human

    Entrez Gene: 3284 Human

    Entrez Gene: 15492 Mouse

    Entrez Gene: 15494 Mouse

    Entrez Gene: 29632 Rat

    Entrez Gene: 360348 Rat

    Entrez Gene: 682974 Rat

    Omim: 109715 Human

    SwissProt: P14060 Human

    SwissProt: P26439 Human

    SwissProt: O35469 Mouse

    SwissProt: P24815 Mouse

    SwissProt: P26149 Mouse

    SwissProt: P26150 Mouse

    SwissProt: P22071 Rat

    SwissProt: P22072 Rat

    SwissProt: Q5FVK0 Rat

    SwissProt: Q62878 Rat

    Unigene: 364941 Human

    Unigene: 654399 Human

    Unigene: 140811 Mouse

    Unigene: 14435 Mouse

    Unigene: 158717 Mouse

    Unigene: 482364 Mouse

    Unigene: 109394 Rat

    Unigene: 128814 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

    HSD3B1属于滋养层细胞标记物(也包括hPL、hCG、Mel-CAN、p63、HLA—G、CK18和inhibin-α) 在很多肿瘤及正常内分泌组织中表达也很高。
    产品图片 HSD3B1滋养层细胞抗原3β-HSD抗体
    Paraformaldehyde-fixed, paraffin embedded (Rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HSD3B1) Polyclonal Antibody, Unconjugated (bs-3906R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
    HSD3B1滋养层细胞抗原3β-HSD抗体
    Paraformaldehyde-fixed, paraffin embedded (Rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HSD3B1) Polyclonal Antibody, Unconjugated (bs-3906R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.

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